Lyophilization is a freeze drying process used for the removal of
water from the final product. In Lyophilization output product freeze
under high vacuum. Lyophilization process is used in the
biotechnological and pharmaceutical manufacturing industries for the
production of good quality products with expanded lifespan. It is
also used to reduce damage of high sensitive products such as
vaccines, proteins, blood plasma, antibodies, and enzymes.
Fluctuation in the properties of protein drugs is a major limitation
and has direct effect on drug delivery. Proteins with therapeutic
activity must be stored at specific temperatures and humidity to
maintain therapeutic properties or drug efficacy until distributed.
Liquid drugs have proteins as active ingredients and are required to
be stored in a refrigerator until dispensed. The requirement of
refrigeration for protein products referred as cold chain. Protein
drugs can also be formulated as lyophilized or powder products.
Lyophilized proteins must be reconstructed before injection.
Lyophilized medicines are sold with reconstruction vial systems, or
packed in specific injection devices (for example two-part syringes,
needle free injectors, pens, etc.) that permit reconstruction of the
lyophilized products to take place in the device before injection.
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Technical developments and increasing risk of contamination of
sensitive pharmaceutical products are factors hampering the growth of
the global lyophilized injectable drugs market. Pharmaceutical
industries find it quite difficult to prevent damage and maintain the
efficacy & functions of a drug product. Moreover, increase in the
number of commercially available injectable drugs and vaccines for
several disease conditions and rise in demand for outsourcing
activities and contract manufacturing in the pharmaceutical
industries are factors projected to boost the growth of the global
lyophilized injectables drugs market in the next few years.
The global lyophilized injectable drugs market can be segmented based
on type of packaging, delivery, indication, end-user, and region. In
terms of type of packaging, the global market can be categorized into
single use vials, point-of-care reconstitution, specialty packaging,
drugs for sc/im injection, drugs for infusion, and product specific
devices. Based on delivery, the global lyophilized injectable drugs
market can be divided into prefilled diluent syringes, proprietary
reconstitution devices, single-step devices, and multi-step devices.
Based on indication, the market can be classified into autoimmune
diseases, infectious diseases, metabolic conditions, and others. In
terms of end-user, the global lyophilized injectable drugs market can
be categorized into hospitals, ambulatory surgical center, specialty
clinic, and others.
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Geographically, the global lyophilized injectable drugs market can be
segmented into North America, Europe, Latin America, Asia Pacific,
and Middle East & Africa. Each region is sub-divided into
countries or sub-regions such as the U.S., Canada, the U.K., Germany,
Brazil, China, India, and GCC Countries. North America dominated the
global lyophilized injectable drugs market due to highly developed
health care infrastructure and increase in demand for advanced
medical technology in the U.S. Europe is another major market for
lyophilized injectable drugs due to development of novel technologies
pertaining to lyophilization in order to enhance the product
portfolio and increased number of clinical trial activities.
Additionally, ample skilled workforce propels the global lyophilized
injectable drugs market in Europe. Asia Pacific is considered to be
the most attractive market during the forecast period due to growing
health awareness and demand for advanced medical technology.
Key players operating in the global lyophilized injectable drugs
market are B. Braun Melsungen AG, Becton, Dickinson and Company,
Baxter International Inc., Hospira (Pfizer), SHL Group, and Schott
NYC, among others. These players have adopted various growth
strategies such as collaborations, partnerships, agreements, and new
product launches to gain competitive advantage in the market.
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