Ileostomy Market is Forecast to Reach US$1.65 Bn by 2024 and Exhibits a CAGR of 8.9%

Global Ileostomy Market: Snapshot

Ostomy is a surgical procedure which creates an opening in the human body to discharge body wastes. This opening which protrudes from the abdominal wall is called as the stoma. There are two ways ostomy is done, one is permanent and one is temporary. The ostomy procedure helps in the treatment of various diseases of urinary and digestive systems. The organs for ostomy are colon, rectum, bladder, and small intestine. Small Intestine is also called ileum.

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In case of ileostomy stoma is created in small intestine (ileum) which bypasses colon, anus, and rectum. An appliance or bag is used to collect all the waste from ileum. Major applications of ileostomy are in the cases when the rectum or colon are not working properly due to diseases like colon cancer, rectal cancer, familial polyposis, inflammatory bowel disease (IBD), intestinal birth defects, intestinal accident, and intestinal emergency. Ileostomy procedure is carried out in the case of removal of whole or part of colon or large intestine. The global Ileostomy market was valued at US$765.2 mn in 2015 and is anticipated to reach US$1.65 bn by 2024, expanding at a CAGR of 8.9% from 2016 to 2024.

Patients to Continue Preferring Hospitals for Ileostomy

Based on procedure, the global ileostomy market is bifurcated into ileostomy and loop ileostomy. In loop ileostomy, ileum (small intestine) in pulled out through stoma, whereas, in end ileostomy colon and sometimes rectum is pulled out through stoma. Of the two segments, the end ileostomy accounted for the larger market share in 2015 and is expected to remain the dominant segment due to its rising application in the treatment of highly prevalent inflammatory bowel diseases. In fact, the segment is likely to showcase a higher CAGR during the forecast period.

Besides the aforementioned segments, the report covers the global ileostomy market based on end users such as ambulatory surgical centers, research centers, and hospitals. Of these, hospitals constituted the leading segment with a share of 55.2% in the global market in 2016. The segment is also prophesized to remain dominant through the forthcoming years, as patients will continue preferring hospitals due to the convenience of the organized set-up and availability of advanced procedures in hospitals. Furthermore, doctors and other therapeutic requirements are more easily accessible in hospitals, which make them more preferred among patients for surgical procedures. However, during the forecast period, the ambulatory surgical centers segment is expected to report a higher CAGR.

Based on equipment, the global ileostomy market is segmented into stoma bags, support belts & girdles, adhesive remover sprays, and protective stoma guards. Of these, stoma bags emerged dominant in the market in 2015. Among the segments based on disease condition type, the market was led by cancer in the same year.

Europe to Remain Dominant Regional Market; Asia Pacific to Report Higher CAGR

Regionally, the global ileostomy market is segmented into Europe, North America, Latin America, Asia Pacific, and the Middle East and Africa. Among these regions, Europe held the leading share of 43.2% of the global market in 2015. The region boasts a well-developed healthcare infrastructure, which had aided the expansion of the ileostomy market in Europe. Besides this, several leading companies are domiciled in Europe, who are also gaining from the region’s favorable healthcare policies. Spurred by these factors, Europe is expected to remain a lucrative market for ileostomy. However, during the course of the forecast period, Asia Pacific is expected to outperform Western countries in terms of CAGR.

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Major players operating in the ileostomy market includes Smith & Nephew, Convatec Inc., 3M Healthcare, B. Braun Melsungen AG, Coloplast, Hollister Incorporated, Salts Healthcare, Flexicare Medical Ltd., Marlen Manufacturing, and Pelican Healthcare.

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Geriatric Medicines Market is Expected to Reach US$948 Bn by 2023 Due to Rise in Aging Population

Geriatric medicine is concerned with the specialist medical care of the frail older individual, and in the promotion of better health in old age. It mainly deals with the prevention, diagnosis, treatment, remedial and social aspects of illness in older people, mainly patients over 65 years of age. The incidence of diseases such as neurological disorder, cancer, rheumatoid arthritis, cardiovascular disorder, and increased use of multiple medicines (polypharmacy) are often leading to medicine-related problems, hence these are augmenting the market for geriatric medicine. The geriatric medicine market is expanding at a promising growth rate globally owing to the rising pace of the aging population, growing prevalence of the chronic diseases, and increased investment in the national healthcare system (developing economies). However, lack of specialized care centers and hospital units could hamper market growth from 2015 to 2023.

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On the basis of therapeutic category the geriatric medicines market is categorized into segments namely: analgesic, antihypertensive, statins, antidiabetic, proton pump inhibitor, anticoagulant, antipsychotic, and others. Among these segments, analgesic accounted for the largest market share in 2014 in terms of revenue and continues to dominate the market during the forecast period. It is approximately estimated that 60%–75% of people over the age group of 65 are reported with at least some persistent pain, the most frequent pain complaints among older people are osteoarthritic back pain, especially in the low back pain, musculoskeletal pain, peripheral neuropathic pain, and chronic joint pain. The leadership of this segment is attributed due to increase in the chronic diseases, favorable government initiatives toward geriatrics and increase in health care infrastructure is likely to boost market growth. Statin is considered to be second-line treatment for cardiovascular disorders and diabetes. Hence, increased incidence of heart attacks, stroke, rheumatoid heart disease, change in lifestyle, and obesity is expected to accelerate market growth in the near future.

On the basis of condition the geriatric medicines market is segmented into cardiovascular, arthritis, neurological, cancer, osteoporosis, respiratory, and others. Cardiovascular holds the largest market share in 2014 in terms of revenue and continues to lead during the forecast period. The total number of inpatient for cardiovascular operations and procedures has increased by 28% from 2000 to 2012 as per the National Heart, Lung, and Blood Institute. With the rising aging population and obesity increases the risk of heart attacks and strokes support the growth of this segment.

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Abbott Laboratories, Inc., AstraZeneca plc, Boehringer Ingelheim GmbH, Bristol-Myers Squibb Company, Eli Lilly and Company, GlaxoSmithKline Plc., Merck & Company Inc., Novartis AG, Pfizer, Inc., and Sanofi S.A are some of the major players operating in the global geriatric medicines market.

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North America Blood Collection Tubes Market: Surge in Number of Complex Surgeries Rises Demand

Blood collection tube is a plastic or glass tube that is without any infection or contamination. These tubes also have a closure, which is evacuated in order to build a vacuum in the interior of the tube, which in turn enables drawing an exact liquid volume from the patient. These tubes are primarily used to collect blood samples. However, they can also be used to collect urine samples as well as serum separator tubes. The North American market for blood collection tubes is gaining traction from a number of factors including the escalating demand from aging population for blood products and increasing number of complex surgical procedures.

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The blood collection tubes market in North America was worth US$300.8 mn in 2014, which is estimated to reach a valuation of US$632.1 mn by 2023, expand at a robust CAGR of 8.6% during the forecast period of 2015 to 2023. The prosperity of this market can be attributed to the vast opportunities available for the players in the form of advanced screening tests, implementation of new blood collection techniques, and advent of automation in the process of collection of blood. These are some of the key factors anticipated to cater a significant demand in the North America market for blood collection tubes across North American countries such as the U.S. and Canada. On the other hand, stringent regulatory guidelines and healthcare policies will also reflect positively on the market during the forecast period as manufacturers are frequently coming up with new and safer technologies in order to collect blood. In addition to that, North America makes for a developed region, and thereby has high level of awareness among the consumers such as hospitals and diagnostic centers. This factor, as well as the subsidies offered by the government in the U.S. and Canada and advancements in blood collection technologies is expected to favor the market in a long-term.

Serum Separating Tubes In-Demand Segment

Based on product type, the global blood collection tubes market has been segmented into herapin tubes, plasma separation tube, EDTA tubes, serum separating tubes, rapid serum tubes, and others. Among these, the serum separating tubes segment accounted for 39.6% shares of the market in 2014, which was a result of utilization of diagnosis purposes across North America and utilization of diagnosis purposes across North America and increasing number of serum samples collected. Serum separating tubes utilize a particular gel that helps in separating blood cells from serum, and also contains particles that cause blood to clot easily. Serum is used to detect the presence of a particular antibody, antigen, hormone, and exogenous substances. Apart from that, the segment of rapid serum tubes is anticipated to increase at a higher rate during the forecast period, which is a result of advent of advanced technologies and incremented efficiency offered by the product.

The U.S. Most Lucrative Market by a Country-mile

The U.S. is the most lucrative country in the North America blood collection tubes market, accounting for 84.6% of the demand, which is primarily a reflection of increasing geriatric population along with the prevalence of various diseases. In addition to that, the increasing government initiatives in the country of the U.S. is expected to drive this market further. For example, introduction of patient protection affordable care act (PPACA) in March 2010 provides healthcare coverage to more than 94% of Americans. Canada is the second most profitable country in the North America blood collection tubes market.

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The North America blood collection tubes market is consolidated with a Becton Dickinson and Company being the pioneer and industry leader with 95% of the market in 2014. With a strong product portfolio of pre-analytical systems, BD is expected to maintain its stronghold in the near future. Terumo Corporation and Qiagen N.V. are some of the other prominent companies operating in this market.

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Introduction of Innovative Devices have Triggered the Demand for Neuroendoscopy Devices Market

Endoscope is a medical device in which a small telescope-like instrument is equipped with high resolution video camera that allows the surgeon to navigate and access tumor. Endoscopy devices are utilized for the diagnosis of almost all kind of cancer. Neuroendoscopy is a minimally invasive procedure in which removal of tumor takes place through small hole in the skull or through nose. Neuroendoscopy is mostly preferred over traditional surgery due to the fact that it enables access in most parts of brain that cannot be done with traditional surgery. Moreover, it is able to remove the tumor without cutting or harming the other parts of skull. Some of the advantages of neuroendoscopy over tradition surgery include less pain than traditional surgery, minimal scarring and faster recovery than traditional surgery. Neuroendoscopy is widely utilized for the treatment of brain tumor that includes acoustic neuromas, skull base tumors, pituitary tumors and metastatic brain tumors.

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The global market for neuroendoscopy devices can be segmented as follows:

By surgery type

> Intra ventricular neuroendoscopy
> Transcranial neuroendoscopy
> Transnasal neuroendoscopy

Intra ventricular neurosurgery is considered as the most promising segment in the global neuroendoscopy devices market. Currently, intra ventricular neuroendoscopy devices market constitutes the largest market share and highest CAGR among all the above mentioned segments. This dominance is witnessed due to large number of neurosurgical procedures performed with these devices, which consequently increases the demand of the devices globally.

With growing number of people undergoing neuroendoscopy procedures the demand of neuroendoscopy devices is also increasing significantly. Moreover, technological advancement in neuroendoscopy devices will further accentuate the global neuroendoscopy devices market. Introduction of innovative devices such as HD camera and sophisticated instrument have triggered the demand for advanced endoscopy devices and this will continue in future. Safety and efficacy during surgery is also a significant market deriving factor associated with neuroendoscopy devices is acknowledged worldwide. Moreover, due to extensive advancement of neuroendoscopy assisted minimally invasive surgical procedure the global market of neuroendoscopy devices witnessing a significant growth. In addition, increasing prevalence of brain tumor also derives the demand of neuroendoscopy devices in the global market.  Moreover, high cost associated with neuroendoscopy devices could pose a threat for the growth of the global endoscopy devices market.

North America and Europe contributed the largest market share in the global endoscopy devices market due to extensive technological advancement in neuroendoscopy devices in these regions. Moreover, strong demand of diagnostic tests accentuates the market growth in North American and European regions. Government initiatives are further expected to accentuate the market growth in these regions. Presently, Asia-Pacific and RoW are considered as untapped market due to lack of proper diagnostic facilities in some remote areas of Asian and African countries. However, Asia-Pacific is considered as an emerging market (forecast period) due to strong economic growth forecasted in some countries such as India, China, Japan and Malaysia which would increase the market share of neuroendoscopy devices in this region.

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Some of the major market players contributing in the global market share of neuroendoscopy devices include Boston Scientific Corporation, Fujifilm Holding Corporation, Hoya Corporation, Olympus Corporation, Boston Scientific Corporation, Karl Storz GMBH & CO. KG, Johnson & Johnson, Given Imaging Inc., Cook Medical Incorporated, Conmed Corporation, C.R. Bard Inc., Arthrex Inc., Aesculap Inc., Accellent Inc.

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Increase in the Proteomics Activities Helps in the Growth for Protein Fractionation Market by 2023

Protein fractionation referred as a process of separation or purification of single or multiple proteinfrom complex mixture of protein based on differences in a specific property of individual component. It is a major step in Proteomics, which is a science of protein analysis. Key limitation of protein and peptide analysis is their heterogenicity in terms of their physiochemical properties. Hence, the protein fractionation technique is very useful tool for protein analysis in various field such as life sciences, and food sciences. Fractionation makes it possible to separate more than two components in a single run. This property sets it apart from other separation techniques.Technological advancement led to high throughput, more resolution, and enhanced sensitivity in the protein fractionation as well as at other stages of protein analysis.

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The global protein fractionation market segmented based on principle of protein fractionation: fractionation by solubility, by cellular location, by charge, by size and fraction by isoelectric point (pI). Geographically, the market segmented into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. North America market was highest market in 2014 due to development of advanced technique for protein fractionation, and well established biopharmaceutical and food industry.However, Asia Pacific and Latin America expected to grow at the faster rate due to growing research base activities primarily in the drug discovery and development area. Protein fractionation by size market dominated in2014 due to application of principle in various techniques, and development of chromatography technique.

Fractionation based on solubility kits separate the protein based on proteins solubility nature and procedure generally involved in this are salt precipitation and detergent solubilization. Kits that separate proteins based on their cellular location are available and separates the protein based on their cell location such as cytoplasm and nuclear protein, membrane proteins, and proteins involved in intracellular membrane signaling pathway and trafficking. Fractionation by charge kits separates the sample, which enriched with the selectively acidic or basic proteins. This separation carried out by ion exchange, electrophoresis, and isoelectric focusing method. Size based fractionation can carried out by dialysis, ultracentrifugation, gel electrophoresis, and gel filtration techniques. Differences in the isoelectric point of protein would be helpful to fractionate the proteins.

The major market drivers for global protein fractionation are increase in the proteomics activities, growing outsourcing of proteomics services, advancement in the biopharmaceutical industry along with plasma protein therapies, and increase in the government and private funding in the emerging countries.Additionally, emergence of new market player boosts the protein fractionation market. However, lower investment by U.S. government in researchactivities to support proteomics would restrict the U.S. as well as global market. Additionally, high cost of advanced instruments, and difficulties to proteomics companies to gain the approval are other restricting factors of global protein fractionation industry. Opportunities for this market lie in the Asian and Latin America market where contract research organization are on high and less regulations than U.S. and Europe.

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Number of companies in the protein fractionation field increased in past few years. However, Major global players in the protein fractionation market are Thermo Fisher Scientific Corporation, Agilent Technologies, and Bio-Rad Laboratories. These companies take the maximum share of the global market. Other players include GE Healthcare Lifesciences, Danaher Corporation, Waters Corporation, PerkinElmer, Luminex, Sigma Aldrich Corporation, and Affymetrix, Inc.

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Cell Phone-Enabled Diagnostics Market Estimated to Flourish By 2023

Most of the low to medium income, developing nations are many times deprived of medical and other healthcare facilities, due to several reasons such as distance between the patient and healthcare service providers and others. Researchers have devised an important solution to this by creating medical diagnostic applications that are really small and can fit into the objects that people are already using in their day to day life. Cell phones were identified as one such object that can bring the hospital to the door or in the hand of the patient. Some of the emerging cell phone-enabled diagnostics include, cell-phone lensfree microscope, cell-phone based imaging using microchip ELISA, mobile phone based clinical microscopy, cell-phone based platform as a biomedical device and telemedicine tools using mobile phone cameras along with paper microfluidics. Some of the examples of these cell phone-based diagnostic tests applications are Roche's Accu-ChekA Glucose Buddy, which is an iPhone application and Arkray's Smart e-SMBG, which is an android application. Tests for sexually transmitted diseases and many other infectious diseases are in huge demand worldwide, which are in their developmental stages at different universities and companies. The cell phone-enabled diagnostics market can be classified into five major segments, namely, cell phone-enabled diagnostics for diabetes, cell phone-enabled rapid immunoassays, cell-phone enabled microscopy, and cell phone-enabled molecular tests.

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Major driving factors for the growth of this market include, technological advancements in diagnostic testing techniques, increasing number of applications of cell phone-based diagnostics, and rising awareness and demand for various cell phone-based technologies. Recent technological advancements have made researchers to think and develop cell phone-based applications that can help in different diagnostic tests. At present, cell phone based diagnostic tests are available for diabetes, histology, hematology, immunoassays and others, which will help grow this market. Rising number of applications of these cell phone-based diagnostics will further boost this market’s growth. Major objective of developing these cell phone-based diagnostics was to reach the underserved population of the world that is mainly located in low to medium income, developing nations. Thus, increasing awareness about such applications along with increasing trend of using smartphones will create more demand for such diagnostics; in turn will contribute towards the growth of this market. However, the cell phone-based diagnostics is still at its nascent stage both in developed as well as developing economies. Future growth will depend both on smartphone industry as well as type of applications for different diagnostic tests installed and utilized by its users worldwide.

Geographically, North America dominates the cell phone-based diagnostics market with highest market share followed by the European market. Major factors responsible for the growth of this market in these regions are high awareness and demand for advanced and point of care diagnostics, high usage of smartphones as well as smartphone based applications in these regions and early availability of newly launched diagnostic applications in these regions. However, other emerging nations located in regions like Asia-Pacific, LATAM and Middle East are expected to grow at a fast pace in near future due to increasing number of smartphone users in most of the developing regions and huge unmet needs of the population present in these regions. Ease of use as well as easy reach in rural areas of these regions of cell phone-based diagnostics will also drive this market’s growth in future. Some of the major players operating in this market are AgaMatrix, Inc., Alere, Inc., ARUP Laboratories, BIO-key International, Inc., CellScope, Inc., Genomic Health, Inc., GenPrime, Inc., GlySens Incorporated, HolGenTech, Inc., Leica Microsystems, Lifescan, Inc., Medtronic, Inc., Oasis Scientific, Inc., QIAGEN and TelCare, Inc.

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Multi-Kinase Treatment Market Outlook 2024: Increasing Occurrence of Cancer Rising the Demand

Global Multi-Kinase Treatment Market: Overview 

Unwanted gene variations on a daily basis may lead to cancer, wherein the body goes on immoderate replication of cells (tumor). With the rising prevalence of cancer, the demand for multi-kinase treatment is all set to rise exponentially. A protein kinase inhibitor controls or blocks the action of one or more protein kinases by adding a phosphate group (PO4) to a protein. Since in the majority tumors, multiple signaling pathways are involved, a large number of inhibitors in clinical development are formulated to impact a wide range of targeted kinases. Multi-kinase treatments are preferred to single target treatments as they are more effective in combating multi-factorial diseases and are needed to circumvent difficulties such as the development of resistance. The advantages and disadvantages of these treatments are gauged on the basis of pharmacokinetics, resistance mechanisms, tumor environment, and selectivity.

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The report offers a comprehensive overview of the multi-kinase industry through important classifications, product definitions, and participants in the industry chain structure. It has been compiled considering and methodically examining multiple facets of the market, including but not limited to trends and opportunities, import and export details, regional markets, and competitive landscape.

Global Multi-Kinase Treatment Market: Drivers and Restraints 

The global multi-kinase treatment market is primarily driven by the increasing occurrence of cancer across the globe. The rapidly growing population and changing lifestyles are contributing to the mounting cases of cancer. The majority of multi-kinase inhibitors are used for advanced cancer conditions such as lung cancer, leukemia, prostate cancer, colorectal cancer, and renal cancer. Since cancer is still incurable in its advanced stages, the possibility of extending the lifespan of patients by at least a year or more is readily accepted by most of the cancer patients. In recent times, the improving healthcare infrastructure is emerging instrumental in providing significant momentum to the global market.

On the flip side, the rising awareness about the side effects of multi-kinase treatment is restraining the growth of the market. These treatments are harmful to the normal functioning of the liver and critical organs such as lungs and kidneys. To mitigate their side effects, these inhibitors are accompanied by other regulators and antibiotics, which might also have negative effects on the liver. However, many recent advances in cancer therapy are ensuring increased efficiency and minimized off-target and systemic side effects.

Global Multi-Kinase Treatment Market: Regional Outlook 

On the basis of geography, the global multi-kinase treatment market is segmented into Asia Pacific, Europe, North America, and Rest of the World. North America is the leading regional market in terms of volume, with the U.S. being a major contributor. The presence of government subsidies is adversely affecting the overall revenue generation in Asia Pacific; nevertheless, the region is estimated to rise at a significant CAGR during the forecast period owing to the presence of immense untapped opportunities. Europe and Rest of the World are expected to expand at a steady pace over the same period.

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Companies Mentioned in the Report: 

The overall market for multi-kinase treatment remains positive as recent developments and innovations by the leading players in this field have already recorded more than 85% success rate. Some of the key players in the market are AstraZeneca plc, Bristol-Myers Squibb Company, C. H. Boehringer Sohn AG & Co. KG, Genentech Inc., Pfizer Inc., GlaxoSmithKline plc, and Novartis International AG.

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