Monday, 4 June 2018

Athlete’s Foot Treatment Market Growth Set to Surge Significantly During 2018 - 2026

Athlete’s foot (Tinea pedis) is a fungal infection, caused by different types of fungi including Trichophyton, Epidermophyton, and Microsporum. The athlete's foot fungus attacks the keratin rich tissues such as skin, nail, and hair. These fungus dwell there because these have enzymatic ability to decompose keratin. Keratin is a fibrous structural protein that is primarily found in nail, hair, and outer layers of human skin. Moreover, these fungus need warm and moist environment for survival and growth. These are commonly found in shower areas of swimming pools and gym. Athlete’s foot is a contagious disease, which can easily spread through contact with infected individuals. Common symptoms of tinea pedis are itching, red blisters between the toes or on the sole, and dry flaky skin on the feet.
Athlete’s foot infection can be diagnosed by detecting the disease symptoms, clinical testing, and a skin lesion potassium hydroxide (KOH) examination. Potassium hydroxide (KOH) examination is the most common test for athlete’s foot. Potassium hydroxide (KOH) destroys the normal cells and leaves the fungal cells undamaged, so that these are easily observed under a microscope. Prevalence of athlete’s foot is higher among in men because they are more exposed to nail trauma due to usage of occlusive footwear. Presently, athlete’s foot affects over 15% of the global population. Athlete’s foot is often treated with over-the-counter (OTC) antifungal medications such as miconazole, terbinafine, clotrimazole, tolnaftate, and butenafine. In March 1999, terbinafine hydrochloride (Lamisil) was the first drug approved for athlete’s foot treatment.
Increase in awareness about fungal infections and rise in incidence of such infections across the world are projected to drive the global athlete’s foot (tinea pedis) treatment market during the forecast period. Additionally, continuously increasing unhygienic environment in populated cities of the world and popularity of over-the-counter antifungal drugs for dermal infection are anticipated to drive the global athlete’s foot (tinea pedis) treatment market in the near future. However, side effects of antifungal drugs such as allergic reactions over the skin, liver damage, and increase in resistance developed by fungi are likely to restrain the global athlete’s foot (tinea pedis) treatment market.
The global athlete’s foot (tinea pedis) treatment market can be segmented based on drug class, route of administration, distribution channel, and region. In terms of drug class, the global market can be categorized into antifungals antibiotics, steroids, and others. Based on route of administration, the global athlete’s foot (tinea pedis) treatment market can be bifurcated into topical antifungals and oral antifungals. In terms of distribution channel, the global market can be divided into online pharmacies, retail pharmacies, and hospital pharmacies.
Geographically, the global athlete’s foot (tinea pedis) treatment market can be segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America is expected to account for the largest share of the global market because of major players concentrated in the U.S. resulting in extensive research and development for developing better drugs. Europe is expected to be the second largest market for athlete’s foot (tinea pedis) treatment during the forecast period, due to rise in prevalence of fungal infection and increase in awareness about new treatment options. The athlete’s foot (tinea pedis) treatment market in Asia Pacific is expected to expand rapidly during the forecast period. Growth of the market in the region can be attributed to increase in awareness about personal hygiene and better access to health care.
Key players operating in the global athlete’s foot (tinea pedis) treatment market are Valeant Pharmaceuticals, Quinnova Pharmaceuticals, Inc., Anacor Pharmaceuticals, Inc., Cardinal Health, Novartis AG, Merck & Co, Inc., Bayer Healthcare LLC, Janssen Pharmaceuticals, Inc., Pfizer, Inc., Medimetriks Pharmaceuticals, Inc., Medicis Pharmaceutical Corporation, and Johnson and Johnson Healthcare.
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Artificial Heart Market Size to Grow Exponentially by 2026

Global Artificial Heart Market: Overview
An artificial heart (or more specifically total artificial heart) can be considered as a prosthetic device implanted into the body to replace the organic mammalian heart. The synthetic replacement in humans acts as a type of mechanical circulatory support system wherein the patient’s native valves as well as ventricles are explanted. The device is usually powered pneumatically. Artificial heart is considered in many ways a technology marvel in clinical history, notwithstanding the many limitations pertaining to functionalities, and is usually used in case of patients suffering end-stage biventricular heart failure awaiting transplantation. In addition, artificial heart is also in demand for patients for whom heart transplantation surgery may not be appropriate. However, they are still to garner noticeable traction in the medical sector, with the implantation done only in a small subset of patients requiring transplantation.
The market for artificial heart is gathering momentum in various parts of the globe, especially in developing and developed nations. With technology advances, artificial heart implantation is increasingly being recommended as a potential treatment in biventricular heart failure.
The report offers evidence-backed insights about the prevailing market dynamics and emerging trends that help assess the potential of the market over the forecast period of 2018–2026. The quantitative and qualitative analyses offered in the study helps in ascertaining the various trajectories of key market segments and assists companies in strategy formulation.
Global Artificial Heart Market: Trends and Opportunities
The rise in global burden of cardiovascular diseases, together with its growing mortality in an aging population, is a key factor underpinning the swift expansion of the artificial heart market. The rising volume of global patient population with end-stage heart failure, including congestive heart failure, coupled with the paucity of transplants available is a crucial factor bolstering the demand for artificial heart. Together with various cardiac-assist devices, artificial heart plays a vital clinical role in managing end-stage heart failure in worldwide patient population. Furthermore, artificial heart is also emerging as a viable option for patients with acute biventricular dysfunction.
Relentless efforts made by researchers and substantial development activities by device makers are focused on increasing the durability of mechanical circulatory support. This has a direct bearing on improving the functionality of these synthetic heart replacement. The lack of timely availability of heart donors is also a key aspect catalyzing the demand for artificial heart implantation.
Several concerns inhibit the commercialization of artificial hearts. The key factor is limited durability and longevity marred by faults, either in membrane or power source. Nevertheless, constant advances being made in design and functionality will expand the therapeutic potential of artificial hearts. Growing number of clinical trials to evaluate the role of total artificial heart as destination therapy in patients who have life-threatening biventricular heart failure is likely to augur well for the expansion of the market.
Global Artificial Heart Market: Regional Outlook
The study presents a comprehensive assessment of regional market dynamics and highlights emerging opportunities and lucrative avenues into which market players can tap into. Some of the key regional markets could be North America, Europe, and Asia Pacific. Developed nations with vast appetite for technology marvels in the medical sector are expected to pose as attractive avenues over the assessment period. Several of them are anticipated to witness rise in government funding to support technology development for artificial hearts.
Global Artificial Heart Market: Competitive Landscape
The report offers a granular assessment of the prevailing competitive landscape and emerging dynamics over the forecast period. To this effect, it takes a closer look at various strategies adopted by top players to consolidate their positions. The study also offers a critical evaluation of the intensity of the competition and the factors shaping the landscape. Numerous makers of artificial hearts in developed nations are also getting substantial backing by venture capital firms to accelerate the launch of their products. Such collaborations are likely to influence the overall strategic dynamics of the market in the coming years.
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Toxicology Testing Services Market is Projected to Reach Over US$ 15 Billion by 2025

Transparency Market Research (TMR) has published a new report titled, “Global Toxicology Testing Services Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026”. According to the report, the global toxicology testing services market is projected to reach over US$ 15 Bn by 2025 expanding at considerable CAGR from 2018 to 2026.


North America is expected to dominate the global market due to the presence of a large number of companies involved in new drug discovery and development activities, stringent regulations by FDA regarding toxicological screening of drugs before entering into human trials, increase in trust and expertise of CROs providing toxicology testing services leading to increase in outsourcing of preclinical procedures, and rise in R&D expenditure of leading companies involved in drug discovery and development process.

In silico toxicology testing methods segment is expected to expand at rapid pace

The report offers detailed segmentation of the global toxicology testing services market based on method and industry type. In terms of method, the market has been segmented into in vivo method, in vitro method, and in silico toxicology testing methods. The in vitro and in silico methods are considered as new approaches to reduce animal use in discovery activities. Thus, these two segments are anticipated to expand at a significantly high growth rate by 2026. These new approaches are considered as reliable, reproducible, faster, and economical options for safety assessment.

Pharmaceutical and biotechnology industries accounted for a major share of the global toxicology testing services market in 2017

Outsourcing of R&D activities to contract research organizations is increasing due to the rise in the number of CROs offering huge portfolio of toxicology testing services at reasonable price. Moreover, these CROs have expertise in this particular areas, which hastens the drug development process, thus benefiting these industries to achieve leading market place in various therapeutic areas. Moreover, due to outsourcing of toxicology studies, these industries are able to focus on their abilities and they accordingly manage their R&D cost. These factors are projected to drive the pharmaceutical and biotechnology companies segment of the global toxicology testing services market.


Market in Asia Pacific is expected to expand at a high CAGR during the forecast period

Expansion of the footprint of leading service providers in Asia Pacific to cover leading players involved in the drug discovery and developments, growing collaborations among drug discovery industries with CROs, and increasing awareness among the consumers in this region regarding toxicity caused by various chemicals, and changing regulatory requirements of the government agencies operating in this region are the factors expected to boost growth of the global toxicology testing services market in Asia Pacific region from 2018-2026.

For instance, in July 2017, Eurofins Scientific, a global leader in bio-pharmaceutical product testing services announced acquisition of Advinus Therapeuticsm, an India-based company engaged in preclinical and clinical phase contract research companies such as Safety Assessment, DMPK, CMC services, and Analytical R&D Services.

Competitive Landscape:

Major players operating in the global toxicology testing services market include Laboratory Corporation of America Holdings, Charles River Laboratories, Inc., Eurofins Scientific, Bureau Veritas, Envigo, Evotec AG, Merck KGaA, SGS Group, Pharmaceutical Product Development, LLC (PPD), and WuXi AppTec.

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Hematology Diagnostics Market to Expand at a CAGR of More than 5.0% from 2018 to 2026

Hematology is defined as the diagnostic classification of cells present in the blood and resulting identification of diseases of the blood-forming organs and diseases of the blood. It includes the calculation of WBC, RBC, and platelets. The analysis for hematologic disorders is related to disease monitoring, prognosis, diagnosis, and screening. Rise in prevalence of blood disorders, technological advancements and introduction of new technically advanced fully automated hematology analyzers, significant demand for laboratory automation, and increase in consolidation among market players and diagnostic laboratories are key factors that are expected to drive the global hematology diagnostics market during the forecast period.


The hematology diagnostics market has been segmented based on product type, end-user, and geography. Based on product type, the hematology diagnostics market has been classified into hematology instruments and hematology consumables. In terms of end-user, the market has been segregated into diagnostic laboratories, hospitals & clinics, academic institutes, and others. Based on geography, the market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.

The research is a combination of primary and secondary research, conducted for understanding and arriving at trends, used to forecast the expected revenue of the hematology diagnostics market in the near future. Primary research formed the bulk of our research efforts with information collected from in-depth interviews and discussions with a number of key industry experts and opinion leaders. Secondary research involved study of company websites, annual reports, press releases, investor presentations, analyst presentation and various international and national databases. The report provides estimated market size in terms of US$ Mn for product, application and geography for the period 2017 to 2026, considering the macro and micro environmental factors. The revenue generated from each product and application was calculated by considering the hematology diagnostics market product sales.


The market report comprises an elaborated executive summary, which includes market snapshot that provides information about various segments of the market. It also provides information and data analysis of the market with respect to market segments based on product type, end-user, and geography. The market overview section of the report analyzes market dynamics such as drivers, restraints, and opportunities that influence the hematology diagnostics market in the current and future scenario. The report also provides the Porter’s five forces analysis, the acquisitions timeline of the hematology diagnostics market companies, SWOT analysis of the market, key vendor and distributor analysis, and comparative analysis of the hematology diagnostics market.

Market share analysis among the market players is analyzed to signify the contribution of these players in the market in terms of percentage share. All these factors will help the market players to decide about the business strategies and plans to strengthen their positions in the global market. Based on geography, the market has been analyzed for major regions: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The study also covers detailed country analysis contributing majorly in the hematology diagnostics market.

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The report also profiles the major players operating in the market and provides various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments. Companies profiled in the hematology diagnostics market report include Abbott Laboratories, Sysmex Corporation, F. Hoffmann-La Roche Ltd., Beckman Coulter, Inc., Bio-Rad Laboratories, Inc., Mindray Medical International Limited, Siemens Healthineers, HORIBA, Ltd., HemoCue AB, and Danaher (Beckman Coulter, Inc.).

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Transparency Market Research is a next-generation market intelligence provider, offering fact-based solutions to business leaders, consultants, and strategy professionals.

Our reports are single-point solutions for businesses to grow, evolve, and mature. Our real-time data collection methods along with ability to track more than one million high growth niche products are aligned with your aims. The detailed and proprietary statistical models used by our analysts offer insights for making right decision in the shortest span of time. For organizations that require specific but comprehensive information we offer customized solutions through adhoc reports. These requests are delivered with the perfect combination of right sense of fact-oriented problem solving methodologies and leveraging existing data repositories.

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Friday, 1 June 2018

Systemic Antiviral Pharmaceuticals Market to Witness a Pronounce Growth by 2023

Global Systemic Antiviral Pharmaceuticals Market
Antiviral drugs are a class of medication that inhibits the development of infection causing viruses. Like antibiotics, specific antiviral drugs are used against specific viruses. As viruses share most of the metabolic processes with the host cell, it is difficult to commercialize new medications that are selective in action. The presently available antiviral agents either act as DNA polymerase inhibitors, reverse transcriptase inhibitors, protease inhibitors, immunomodulators, neuraminidase inhibitors or integrase strand transfer inhibitors.


Global Systemic Antiviral Pharmaceuticals Market: Segmentation

Antiviral drugs can be administered by various methods such as topical or local application, systemic delivery, controlled delivery and targeted delivery. Systemic drug delivery is relatively safe and effective for the treatment than topical agents. In recent times, systemic delivery method is gaining attention owing to its higher therapeutic efficacy and bioavailability. The demand for products with systemic application is high especially in the treatment for chronic viral infections such as hepatitis and HIV infection.

Based on the class of antiviral drugs, the global systemic antiviral pharmaceuticals market is segmented into DNA polymerase inhibitors, reverse transcriptase inhibitors, protease inhibitors, immunomodulators, interferon, neuraminidase inhibitors and integrase strand transfer inhibitors. Increasing resistance to M2 inhibitors has shifted the focus towards neuraminidase inhibitors for the treatment of influenza. Neuraminidase inhibitors class of drugs includes Oseltamivir and Zanamivir which are administered through systemic route. Herpes virus can be treated using medications such as Acyclovir, Brivudin, Cidofovir, Famciclovir, Fomivirsen, Foscarnet, Ganciclovir, Penciclovir, Valacyclovir, Vidarabine and Valganciclovir.

Based on the disease type, the global systemic antiviral pharmaceuticals market can be analyzed as herpes, hepatitis, influenza and HIV infection. Recent advancements in the field of antiviral treatment for herpes infection have inclined the ophthalmologists to treat severe ocular infection caused by herpes virus. In addition, the acute retinal necrosis (ARN) syndrome caused by herpes virus and retinal infection caused by cytomegalovirus is also treated using systemic antiviral drugs. Vidarabine, Acyclovir, Ganciclovir, and Foscarnet are the four major systemic antivral drugs used in the treatment of ophthalmic infections. Rising incidence of herpes virus infections, as well as the rising epidemic of HIV infections has led to increase in ophthalmic infections which drive the demand for systemic antiviral pharmaceuticals.


Global Systemic Antiviral Pharmaceuticals Market: Geographical Dynamics

The demand for systemic antiviral pharmaceuticals is high in regions with high prevalence of herpes, influenza, hepatitis and HIV infection. According to World Health Organization (WHO), worldwide 35.3 million people were living with HIV infection at the end of 2012. The prevalence is high in the African region where nearly one in 20 adults is living with HIV infection. Further, the prevalence of herpes simplex virus type 2 is high in Africa, North America and some parts of Asia-Pacific. Early and effective treatment is therefore the primary need in these regions. Hence, the demand for systemic antiviral pharmaceuticals will increase with growing incidence of viral infections.
Some of the major players in the systemic antiviral pharmaceuticals market are GlaxoSmithKline plc, Bristol-Myers Squibb, Gilead Sciences, F. Hoffmann-La Roche Ltd., Pfizer, Inc., Boehringer Ingelheim, Abbott Laboratories and Merck & Co., Inc.


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Bleeding Disorder Therapeutics Market Share and Growth Factors Impact Analysis 2016 - 2024

Global bleeding Disorder Therapeutics Market: Overview
Bleeding disorders usually include symptoms in which delay in the blood clotting process can be observed. Two main types of blood disorders include von Willebrand disease and hemophilia, both of which are hereditary in nature. Von Willbrand is one of the most common congenital bleeding disorders in humans, caused as a result of deficiency of Von Willebrand factor (VWF) which assists in clot clotting process. There are three types of Von Willebrand disorders classified on the basis of level of VWF synthesis. Von Willebrand disorder’s occurrence is almost equal in both sexes, and affects about 1% of the general population according to the Centers for Disease Control and Prevention (CDC).
The most common complications of the disorder include heavy menstrual bleeding, excessive gum bleeding and abnormal bleeding after minor injuries. Hemophilia, on the other hand, is a disorder in which clotting factors essential for clotting phenomenon are inadequate or absent. In the U.S. about 400 newborns suffer from hemophilia every year according to statistics published by the CDC. The two main types of hemophilia are hemophilia A with deficiency of clotting factor VIII and hemophilia B with deficiency of clotting factor IX. The National Heart, Lung and Blood Institute, U.S. details that approximately 7 out of 10 individuals who suffer from hemophilia A have severe form of the disorder.
Global bleeding Disorder Therapeutics Market: Drivers and Restraints
Although bleeding disorders cannot be cured, various medications are directed to manage the symptoms of the disorder. Medications may be prescribed before or after surgery, dental work or after an injury to patients suffering from mild form of the disorder. Severe form of the disorder can be controlled with daily medicines prescribed by the doctor. The market for bleeding disorder therapeutics is driven by the large customer base, increased awareness about the bleeding disorders and available cures, and favorable reimbursement policies. The market will be seeded with new drugs emerging from a promising pipeline.
Moreover, patent expiry of existing brands will also provide generic drug manufacturers opportunities to enter the lucrative bleeding disorder therapeutics market. Due to the high price of branded drugs, the market for bleeding disorder therapeutics is mostly concentrated towards western countries of North America and Europe. Low cost drugs will help in better market penetration in under developed and developing economies where patients cannot afford high cost of medical treatment. Hence availability of low cost generic drugs will boost market growth in the countries of Asia-Pacific, Latin America, Middle East and Africa.
Global bleeding Disorder Therapeutics Market: Competitive Dynamics
A few drugs that have lost their patent protection include NovoSeven by Novo Nordisk, whose patent expired in Japan and in the U.S., in 2009 and November 2010, respectively, while the European patent expired on a country-by-country basis in 2011, Plavix by Bristol-Myers Squibb, Lovenox by Sanofi, Neupogen by Amgen, and Procrit by Janssen. These drugs are now available in the market in generic cost effective form. Companies are also trying to discover gene therapy which can cure the disorder. Some of the players conducting lineal trials are Biogen Idec, Novo Nordisk, Bayer Healthcare, Xenetic Biosciences, Cangene Corporation, CSL Behring, Alnylam and Pfizer.
The global bleeding disorder therapeutics market is highly competitive and fragmented. Technological advances will expand the boundaries of the market by adding new products. In 2014, Baxter International, Inc. agreed to acquire Chatham Therapeutics. The acquisition will give Baxter Chatham's developmental gene therapy program which is directed toward of treatment of hemophilia.
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Analgesics Market Competitive Landscape Analysis with Forecast by 2024

Global Analgesics Market: Overview
Analgesics, or painkillers, are used to reduce and treat aches and pains. Internal and external analgesics are used to combat pain resulting from inflammation, cancer treatments, physiological injury, neuropathic conditions, surgeries, wounds, and phantom aches. The most prominent therapeutic classes of analgesics are local anesthesia, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids. The growing incidence of cancer worldwide and the rise in chronic diseases are mainly responsible for the consistent growth of the global analgesics market.
The research publication offers clients a comprehensive summary of the global analgesics market and elucidates the various factors driving and hampering its growth during the forecast period. The report also evaluates the chief players competing in the global market for analgesics and profiles them on the basis of a number of key attributes, such as company and business overview, recent developments, product portfolio, business strategies, and financial strength.
Global Analgesics Market: Key Trends and Competitive Landscape
The increasing therapeutic benefits offered by analgesics, in addition to effective and fast relief from pain, have significantly driven the demand for analgesics over the years. The development of innovative drugs and rising awareness about these treatment options have also supported the analgesics market. Moreover, the rise in recurring aches and pains owing to an increase in the prevalence of cancer, cardiovascular disease, arthritis, and other chronic and acute diseases has propelled the demand for analgesics. Other key factors positively impacting the global analgesics market include the growing prevalence of pain worldwide, the rise in effective treatment options, a surge in the aging population, and the growing acceptance of analgesics by a wider target audience.
Eli Lilly and Company, Teva Pharmaceutical Industries Ltd., Bayer AG, F. Hoffmann-La Roche Ltd., Pfizer Inc., Endo Pharmaceuticals, Reckitt Benckiser plc, Bristol-Myers Squibb, Sanofi, Johnson & Johnson, Novartis AG, and GlaxoSmithKline PLC are some of the major companies actively participating in the global analgesics market. In the quest of increasing their share in the analgesics market, an increasing number of firms have been adopting acquisitions as their main development strategy.
Global Analgesics Market: Region-wise Outlook
The global analgesics market has been categorized into Europe, North America, Asia Pacific, and Rest of the World based on geography. North America is presently the leading market for analgesics and is projected to retain its dominant position through 2024. Recent regulatory changes in the U.S., accompanied by new marketing strategies by analgesics companies, have greatly benefited this regional market. After declining sales owing to frequent recalls, the analgesics market in the U.S., in particular, has been stabilizing on account of the return of prominent brands, the rising occurrence of aches and pains, the rise in the average age of the population, and an alarming rate of obesity. These demographic and lifestyle developments have significantly propelled the North America analgesics market.
The Europe analgesics market is also anticipated to expand in the coming years owing to the rapid commercialization of new drugs and an increasing geriatric population. Although analgesics form one of the largest product areas in over-the-counter drugs, this segment has been negatively affected by the growing trend of improving health instead of merely treating symptoms. An increasing number of consumers in the U.K., for instance, have restricted their consumption of analgesics with this trend in mind, thereby negatively impacting the sales of analgesics.
In contrast, consumers in several Asia Pacific countries seem relatively less concerned over the possible side-effects of analgesics. A higher willingness to self-medicate instead of visiting a trained physician for mild pain and fever is a trend that is common in a number of countries, more prominently in India. Moreover, the immensely stressful lifestyles in most urban parts of the region have resulted in consumers looking for quick and easy solutions to combat pain. This, combined with the surge in purchasing power, has enabled the demand for as well as sales of analgesics to remain steady over the years.
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