Combination Drugs Diagnostics Market

Combination drug also referred to as fixed dose combination (FDC), is a formulation which includes two or more active pharmaceutical ingredients (APIs). The dosage is distributed in certain fixed doses. Initially, fixed dose combination products were produced for targeting single diseases for example antiretroviral combination drugs were manufactured for targeting AIDS. However, with the advancements, in research and development activities currently combination drugs are being manufactured for targeting multiple disease conditions such as Exforge (amlodipine/valsartan) or Caduet (atorvastatin/amlodipine). Improved medication compliance by reducing the pill burden of patient and ability to compose combined profiles (pharmacokinetics, adverse effects and effects) that may be limited to single dosage form are some of the advantages associated with uptake of combination drugs.

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Factors such as increase in geriatric population, investment in R&D and improved understanding of the nature of diseases are driving the combination drugs diagnostic market growth globally. Since, aged population is more prone to infectious disease therefore; increase in geriatric population will likely increase the demand for combination drugs diagnostics market worldwide. Additionally, as per the World Health Organization, by 2020 nearly 14.1% of the world population will suffer from neurologic disorders which would further lure manufacturers for the production of combination drugs. Similarly, as per American Diabetes Association, in 2011 25.8 million Americans were diagnosed with diabetes and total cost of treatment reached USD 245 billion. Hence, to effectively address the needs of patients, combination drugs are being launched in the market. Atripla, Combivir, Kaletra, Truvada, Trizivir, Excalia, Symbax, Contrave, Symbicort, Advair/ Seretide, Flutiform, Janumet, Duovent, Berodual, Augmentin, Bacterin, Primaxin, Zosyn and others are some of the popular combination drugs available for the treatment of various disorders.

The market for combination drugs diagnostics market can be analyzed on the basis of products and applications of fixed-dose combination drugs. Combination drugs are utilized for the treatment of cardiovascular disease (hypertension and hypercholesterolemia) and infectious diseases (acquired immunodeficiency syndrome, bacterial infections, HIV infection, Helicobacter pylori and tuberculosis). The FDCs are also utilized for the treatment of diabetes, psychiatric disorders (Alzheimer’s disease and depression) and respiratory diseases (COPD and Asthma).  Some of the combination drugs are also used as oral contraceptives, vaccine products and radioactive combination drugs.

Geographically, North America is witnessed to be the largest regional players for combination drugs diagnostics market. The region accounts for more than 30% share of the global combination drugs market. The dominance of this region is witnessed due to extensive research and development activities and presence of major market players in this region. Moreover, increasing awareness among people about diabetes, cardiovascular diseases and government initiatives will further accentuate the combination products market in this region. Europe held the second largest share for combination drugs diagnostics market followed by Asia-Pacific and Rest of the World. Asia-Pacific is considered as an emerging market due to strong forecasted economic growth (healthcare infrastructure, healthcare facility and product expansion) in some Asian countries such as India, China, Japan and Malaysia.

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Some of the major players of the global combination drugs diagnostic market include Merck, & Co, Inc. AstraZeneca Plc, Bristol Myers Squibb, Orexigen Therapeutics, Astellas Pharma, Vivus, Roche Diagnostics, Bayer AG, Sanofi, Novartis AG, Pfizer Inc. and others. These players have worldwide presence and are involved in constant competition with each other. Hospitals, private clinics, patients and physicians are major customers for combination drugs.

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Powder Metallurgy Sector to Set the Bar for a Tangible Growth in Sintering Process Market

Global Sintering Process Market: Brief Account 

The global sintering process market is marked by innovations and new product developments. High speed sintering (HSS) invented by Neil Hopkinson leading the 3D printing department of Xaar, an inkjet printhead manufacturer, is expected to have a key role to play in the accomplishment of the company’s 2020 vision. Apart from acquisitions and partnerships, Xaar will look to capitalize on the fast growth of 3D printing to double its revenue by 2020. The invasion of HSS in 3D printing is likely to make the process competitive with injection molding and other mass manufacturing technologies.

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Application and end user are predicted to be crucial classifications of the global sintering process market. Participants could count on the various applications and end users of the sintering process to ensure an impressive growth rate.

The report offered herewith is a comprehensive study of the global sintering process market, providing a detailed account of drivers and restraints, growth opportunities, geographical segmentation, and competitive landscape that are in the best knowledge of expert research analysts.

Global Sintering Process Market: Trends and Opportunities 

The powder metallurgy sector is anticipated to set the bar for a tangible growth in the world sintering process market. The quality of different physical properties lent by this technique to sintered parts and the processing cost involved are expected to play a significant part in the growth of the world sintering process market. In fact, these are the primary parameters based on which the efficiency of the sintering process is assessed. A variety of sectors such as construction, machine tool and power, automotive, electrical and electronic, defense, and aerospace employ sintered metals at a telling degree. Although non-ferrous and ferrous metals are commonly used in the sintering process, ceramics, cermets, and rare earth intermetallics are also sintered.

Replaceable technologies could pose some threat to the world sintering process market on account of the harmful effects of the process on the environment and human health. Besides this, there are a multitude of government laws laid down regarding the usage of the process. However, various end-user applications of the sintering process in a wide range of industries owing to technological developments are envisaged to help the world sintering process market dissolve the effect of its deterrents.

Global Sintering Process Market: Geographical Analysis 

The international sintering process market in Asia Pacific is envisioned to benefit from the stupendous rise of the construction and automotive sectors. Indonesia, China, India, and other developing economies of Asia Pacific could raise the hopes of players operating in the regional sintering process market. Stringent government regulations pertinent to the application of the sintering process are foretold to lead a downward growth trend in Europe and North America. Howbeit, the Asia Pacific sintering process market advantaged with aggressive technological and industrial development could prepare a fertile ground of growth for players to ride on.

The demand in the international sintering process market is predicted to augment with the need for an effective industrial technique to enhance the capabilities of a diverse range of metals. The analysts foresee the international sintering process market to be solely stimulated by the powder metallurgy sector, although the growth is prognosticated to remain stable over the course of the forecast period.

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Global Sintering Process Market: Companies Mentioned 

Among other key companies, Pacific Sintered Metals and GKN Sinter Metals involved in the manufacture of sintered metal parts are prophesied to outshine in the worldwide sintering process market. The authors of the report have unveiled some important elements for players to sustain their competitiveness in the worldwide sintering process market.

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Electrical Stimulation Devices Market to Reach US$6.5 Bn by 2023 with a CAGR of 6.0%

Electrical stimulation devices deliver alternating, direct, or pulsating waveform forms of energy for providing a therapeutic effect to the body. This study provides market analysis for various electrical stimulation devices that are used within home care and hospital settings. The stakeholders of this market study comprise established electrical stimulators product manufacturers, and distributors as well as new participants who wish to enter the global electrical stimulation devices market.

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The rise in the incidence of spinal injuries and low back pain, as well as their increasing usage in sports medicines, has boosted the demand for electrical stimulation devices (ESDs) substantially across the world in the recent times. The growing prevalence of chronic conditions such as diabetes and obesity has also fueled their demand considerably and is likely to continue to do so over the years to come.

According to TMR, the opportunity in the global ESDs market was worth US$3.8 bn in 2014. Rising at a CAGR of 6.0% during the period from 2015 to 2023, it is estimated to reach US$6.5 bn by 2023.

Neurological and Movement Disorder Management to Witness Fastest Growth in Demand for ESDs

Pain management, musculoskeletal disorders management, neurological and movement disorder management, incontinence management, metabolism and GIT management, and other applications such as training, esthetics, and cosmetics are the prime application areas of ESDs. Among these, pain management reported the strongest demand for ESDs in 2014 with demand share reaching 53.4%. The rising incidence of chronic pain, low back pain, and spinal injuries among people and the growing number of clinical trials supporting the usage of ESDs in these conditions have fueled the demand for ESDs in the pain management segment.

Analysts at TMR anticipate the pain management segment to remain the key consumer of ESDs throughout the period from 2015 to 2023. However, the neurological and movement disorder management segment, expanding at a CAGR of 7.40% between 2015 and 2023, is likely to witness the fastest growth in the demand for ESDs.

Demand for ESDs to Remain High in North America

Regionally, North America, Asia Pacific, Europe, Latin America, and the Middle East and Africa are the main segments of the global market for ESDs. In 2014, North America led the overall market with a share of 43.5%, making US$1.6 bn in revenues. The region is expected to retain its leadership in the years to come on account of the rising prevalence of lifestyle-related diseases, the increasing cases of sports injuries, the growing access to healthcare, and the escalating incidence of pain indications among elderly patients.

Asia Pacific, however, is anticipated witness the fastest adoption of ESDs at a CAGR of 6.90% during the period from 2015 to 2023. The rapid rise in the geriatric population and the growing prevalence of spinal injuries, age-related chronic neck and back pain, and neurological disorders are likely to boost the application of ESDs in the region in the near future.

Along with these, the escalating disposable income of the people and the improved life expectancy in this region are also projected to fuel the demand for ESDs in Asia Pacific over the next few years.

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The top three manufacturers of electrical stimulation devices are Medtronic Plc., St. Jude Medical Inc., and Boston Scientific Corp. Collectively, they accounted for a share of more than 70% in the global electrical stimulation devices market in 2014. Zynex Inc., Uroplasty Inc., NeuroMetrix Inc., Nevro Corp., DJO Global Inc., Cyberonics Inc., and BTL Industries Inc. are some of the other prominent participants in this market.

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Rising Incidence of Coagulation Disorders Drives Heparin Market to Reach US$14.3 by 2023

Heparin is an injectable blood thinner, utilized for the treatment of deep vein thrombosis (DVT) and pulmonary embolism. It is also employed as part of the treatment of unstable angina and myocardial infarction. The increasing incidence of coagulation disorders is propelling the demand for heparin significantly across the world.

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The global heparin market has been analyzed on the basis of product in this research report. Ultra-low molecular weight heparin (ULMWHs), low molecular weight heparin (LMWHs), and unfractionated heparin are the major products available in the worldwide heparin market. ULMWHs has been the most commonly used heparin over the past decade. However, the increasing overall cost of ULMWHs is likely to hamper the growth of this market segment in the near future, states the research report.

The report also studies the global heparin market on the basis of its regional spread. According to the study, Europe, North America, Asia Pacific, and the Rest of the World are the prime regional markets for heparin.

Europe dominated the global heparin market in 2014, while North America occupied the second position. The rising incidence of coagulation disorders in North America and Europe is driving these regional markets significantly.

In addition to this, the growing prevalence of deep vein thrombosis (DVT), spurred by the rapid increase in the geriatric population, leading to cancer, heart failure, and obesity is likely to drive the demand for heparin in these regions over the forecast period, notes the research study.

The heparin markets in Asia Pacific and the Rest of the World are also expected to exhibit healthy growth during the forecast period on account of the presence of a largely untapped market. Analysts at TMR anticipate the economic growth, the infrastructural development in the healthcare sector, and the rising number of surgical procedures in these regions to fuel the demand for heparin significantly in the coming years.

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Teva Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., LEO Pharma A/S, Fresenius Kabi AG, Mylan N.V., Sanofi S.A., Pfizer Inc., and Syntex S.A. are some of the key participants in the global heparin market profiled in the report.

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Bone Grafts and Substitutes Market is Expected to Reach US$3.48 Bn by 2023, Expanding at 4.5% CAGR

Bones have a natural tendency to heal, however if the defect surpasses a critical size, then bone grafting is the preferred option. Bone grafting is a surgical procedure that replaces the missing or damaged bone by natural or synthetic bone. There are three major types of bone grafts: autografts, allografts, and bone substitutes. Bone grafts and substitutes should be biocompatible, osteoconductive, osteoinductive, structurally similar to bone, easy to use, and cost effective. Autogenous bone grafts contain osteoblast and endosteal osteoprogenitor cells for regenerating the new bone. Although autografts are considered gold standard for bone grafting, major disadvantages associated with autografts are limited supply and high donor site morbidity rate.

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Increasing Arthritis Surgeries will Fuel Demand from Spinal Fusion Segment

By application, the global bone grafts and substitutes market is segmented into long bone, spinal fusion, foot and ankle, joint reconstruction, and craniomaxillofacial. Of these, the spinal fusion application segment held the largest share in the market in 2014. The rising demand for minimally invasive surgeries and the increasing geriatric population around the world are the key factors fuelling demand from this segment. The increasing number of fatal and non-fatal accidents, coupled with the rising arthritis surgeries will also support growth of this segment. As per TMR, the spinal fusion segment is expected to rise at a CAGR of 4.4% between 2014 and 2023.

Besides this, the use of bone grafts and substitutes is also expected to increase in joint reconstruction surgeries. These surgeries are mainly conducted to restore the form and function of the body part affected by infection, tumor, or other diseases. The rising awareness about the effects of joint problems and benefits offered by surgeries in relieving pain will fuel demand from this segment in the forthcoming years.

North America Dominates Global Market, Asia Pacific to Report High CAGR

Regionally, North America held the largest share in the global bone grafts and substitutes market in 2014. Several leading companies are located in this region, making this region a hotbed of innovation. Launch of novel therapeutics is higher in North America than most other regions, besides which the region is also witnessing an increasing number of road accidents. These are the key factors fuelling sales of bone grafts and substitutes in North America. Furthermore, the increasing geriatric population will fuel the number of orthopedic surgeries conducted in the region. This will in turn bolster demand for bone grafts and substitutes. As per TMR, the North America bone grafts and substitutes market is expected to reach US$1.23 bn by 2023.

In Europe, the bone grafts and substitutes manufacturers will witness rising demand in countries such as Germany, Spain, Italy, France, and the U.K. However, TMR forecasts, the Asia Pacific market to exhibit remarkable growth during the forecast period. The rising medical tourism across countries such as India, China, Malaysia, Singapore, and Thailand, will prove lucrative for the manufacturers of bone grafts and substitutes in the region. Stringent medical device regulations in South Korea, Japan, and China will limit foreign competition, thus bolstering sales opportunities for the domestic players.

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Some of the leading players operating in the global bone grafts and substitutes market are Stryker Corporation, Zimmer Inc., Medtronic PLC, Wright Medical Group, Inc., DePuySynthes, AlloSource, and Nuvasive, Inc.

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Rising Prevalence of Diseases Prompts Progress in Canada Home Healthcare Market

Canada home healthcare market represents a wide range of home medical devices and services to support patients with chronic disease conditions. The risk and prevalence of chronic and lifestyle related diseases are constantly increasing in Canada which would drive the acceptance of home medical devices and services, consequently leading to the growth of the market. Moreover, changing demographics in Canada further supports the growth of Canada home healthcare market. Statistics Canada projected that around 5 million people in Canada were aged over 60– 65 years in 2011 and the number is expected to double in the next 25 years (10.4 million). Such change in demographics will shift a substantial portion of population to the higher risk level for illnesses that demand continuous medical intervention. Thus, this factor would in turn increase the utilization of home healthcare devices and services hence driving the market growth. Moreover, advancement in technologies, increasing sedentary lifestyle and growing preference for alternatives to hospital based long-term care also supports the Canada home healthcare market growth. However, high costs coupled with strict regulatory environment restraints the market growth. The Canada home healthcare market is estimated to be USD 10,449.1 million in 2013 and is expected to reach USD 18,939.9 million by 2020, growing at a CAGR of 8.9% from 2014 to 2020.

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According to the report, the Canada home healthcare market is primarily driven by the rising number of patients who suffer from ailments such as diabetes, arthritis, cancer, and multiple chronic diseases. This rising prevalence of diseases, coupled with a growing population of geriatric Canadian citizens, is boosting the Canada home healthcare market at a rapid rate.

Other drivers of the Canada home healthcare market include technological advancements that allow for a more efficient healthcare service that can be delivered at an optimum time, and a growing awareness of citizens towards the Canada home healthcare market and its services.Between the different segments of the Canada home healthcare market according to type, the market is led by diagnostics and monitoring devices, a segment that held over 30% of the market in 2013. This segment is boosted by consistent government efforts taken to increase awareness among citizens regarding the existence of diagnostic and monitoring devices and their benefits.

The home mobility segment earned the lowest revenue for the Canada home healthcare market in 2013. This is attributed to the low market cost of the instruments sold in the home mobility segment, such as walkers, crutches, cranes, and rollators.In terms of services, the Canada home healthcare market is led by the segment of telehealth and telemedicine. The segment is progressing at a CAGR of 11.0% by 2020. The telehealth and telemedicine segment generated 2% of the usual revenue recorded in the Canada home healthcare market in 2013. The Canada home healthcare market services are constantly driven by factors such as high cost-effectiveness, easier access to rural locations, and high quality care of patients.

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From a geographical perspective, the Canada home healthcare market was led by the province of Ontario in 2013. At the same time, the Canada home healthcare market in the Quebec is expected to rise at a rapid CAGR of 9.2%. The report cites increasing population of chronically ill people as the key reason for the high growth rate of the Canada home healthcare market in Quebec.Key players involved in the Canada home healthcare market are Home Care Ontario, The Canadian Home Caress, We Care Health Services, GM Healthcare, 3M Healthcare, Omron Healthcare, and Johnson & Johnson.

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Respiratory Disease Testing Market is Anticipated to Reach US$3.14 Bn by 2022 at a CAGR of 3.40%

The global respiratory disease testing market is witnessing a surge in market valuation in the recent years. The rising frequency of respiratory diseases, triggered by the rapid increase in the global geriatric population, has given an impetus to the market in the past. This trend is also expected to boost the worldwide market for respiratory disease testing during the period from 2014 to 2022 significantly.

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The global market for respiratory disease testing is broadly analyzed on the basis of the types of tests performed and the end-use industries. Spirometry tests, imaging tests, peak flow tests, lung volume tests, and blood gas tests are the major test segments of this market while hospitals, clinical laboratories, and physician offices are the primary end users.

Apart from this, the worldwide respiratory disease testing market is also evaluated on the basis of its regional distribution into North America, Latin America, Europe, Asia Pacific, the Middle East and North Africa, and the Rest of the World. The U.S. and Canada drive the respiratory disease testing market in North America. Brazil, Mexico, and the Rest of LATAM lead it in Latin America. The U.K., Germany, and the Rest of Europe are the main markets for respiratory disease testing in Europe. Asia Pacific is driven by the market in China, Japan, and Rest of APAC and the Middle East and North Africa is led by the UAE, Saudi Arabia, and the Rest of MENA.

This research report provides a comprehensive overview of the global market for respiratory disease testing and helps market participants in making significant strategies and crucial decisions for the further development of their businesses.

Overview of the Respiratory Disease Testing Market 

The global market for respiratory disease testing has been continuously showing an impressive rise. In 2013, it stood at a US$2.3 bn. Analysts estimate it to expand at a CAGR of 3.40% during the period from 2014 to 2022 and reach a value of US$3.1 bn by the end of the forecast period.

Among the tests markets, the imaging tests segment led the worldwide market for respiratory disease testing in 2013 owing to the extensive uptake of imaging measures, specifically X-ray. However, the market for spirometry tests is expected to report the highest CAGR over the forecast period. The efficiency of these tests, enhancing the precision in results are projected to boost this market segment in the coming years.

Among end users, the hospital segment emerged as the market leader in 2013 and is likely to maintain its position in the near future.

Among regional markets, North America led the global respiratory disease testing market in 2013. On the other hand, the Asia Pacific respiratory disease testing market is anticipated to exhibit the highest CAGR over the forecast period.

The worldwide market for respiratory disease testing exhibits a positive growth. However, the low adoption rate of advanced spirometers as well as the digital radiography systems is likely to hamper the growth of this market over the next few years.

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Companies mentioned in the research report 

CareFusion Corp., COSMED, Carestream Health Inc., Futuremed America Inc., MGC Diagnostics Corp., GE Healthcare, ndd Medical Technologies Inc., Perkin Elmer Inc., NIHON KOHDEN Corp., Philips Healthcare, Siemens Healthcare, SDI Diagnostics, and Smiths Medical are the major players operating in the global respiratory disease testing market.

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