3D cell culture is a
controlled simulated environment outside of a living organism,
wherein cells are allowed to grow and migrate by interacting within
their habitat. 3D cell culture nurtures levels of cell
differentiation and tissue organization which is not viable in
traditional 2D culture systems. 3D cell culture has more tissue
divergence and cell cohesion properties. 3D cell structures are
gaining popularity and have shown increased applications, especially
in the early drug discovery and other research and development. This
technique is used by researchers to fabricate physiologically similar
cell culture stereotypes that aid drug discovery and development.
Persistent need to refine efficiency in pharmaceutical research and
development is also encouraging the use of 3D cell cultures.
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3D cell culture is
one of the rapidly growing segments in the health care space due to
considerable range of applications in cancer research, in vitro
environment, and regenerative medicine. The ability of 3D cell
culture to strengthen the understanding of tissue maturation and
organization, organogenesis, and cell differentiation has increased
its utility. It has also replaced animal prototypes in clinical
testing and experiments, as these look similar to cells in vivo.
Increase in adoption of 3D cell culture in diagnostic centers,
hospitals, and pharmaceutical and biotech companies, and rise in
demand in organ transplantation, tissue regeneration, and
regenerative medicine. The major drivers of the 3D cell culture
market. Researchers are conducting experiments to advance and develop
better options for culturing cells, and 3D cell culturing presents
various benefits such as gaining better information and helping to
conduct better research. 3D cell structures are relatively thicker.
Hence, these could experience some potential barriers. Cells could
react and emerge differently in 3D cell culture environment. This
would require changes in experiments.
The global 3D cell
culture market can be segmented based on product type, application,
end-user, and region. In terms of product type, the market can be
divided into scaffold-based 3D cell culture (hydrogels /ECM analogs,
micro patterned surfaces, and solid scaffolds), scaffold-free 3D cell
culture (low adhesion micro plates, 3D petri dishes, 3D bioreactors,
and hanging drop plates), microfluidics-based 3D cell culture,
magnetic levitation, and 3D bio printing. Based on application, the
global 3D cell culture market can be classified into drug discovery
and toxicology, cancer and stem cell research, and tissue engineering
& regenerative medicine. In terms of end-user, the market can be
categorized into pharmaceutical & biotechnology companies and
research laboratories and institutes.
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Geographically, the
global 3D cell culture market can be segmented into North America,
Latin America, Europe, Asia Pacific, and Rest of the world. North
America and Europe dominate the market. High market share of these
regions is attributed to rise in prevalence of cancer and increase in
investment in R&D and health care. Moreover, governments in these
regions support advancement in the field of 3D cell culture through
grants and funds. The market in Asia Pacific is expected to expand at
a high CAGR due to increase in demand for 3D cell culture in
developing nations.
Major players in the
global 3D cell culture market are Merck, InSphero, Lonza, Thermo
Fisher Scientific, Inc., ReproCELL, Inc., Nano3D Biosciences, Inc.,
Corning Technologies, Synthecon Incorporated, Global Cell Solutions,
3D Boitek, Kuraray Co. Ltd., Hamilton Company, Mimetas, and QGel.
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