Platelet aggregation is a process where human platelet cells are
involved in hemostasis, bleeding to repair, and vessel constriction.
In addition, in conjunction with other cells they play a crucial role
in the inflammation and other pathological situations. Platelet
aggregation is a biological process which is mediated by a platelet
activation factor (PAF). Platelet aggregation test involves
venipuncture in an appropriate anti-coagulant medium, followed by
centrifugation to produce plasma which is rich in platelets, where
aggregometers are used to study the platelet aggregation. The
inhibitory activity of the compounds is utilized for the assessment.
Platelet function tests find application in pre-surgery tests;
diagnose platelet dysfunction, monitoring anti-platelet therapy etc.
Platelet aggregation is one of the various types of Platelet function
tests. Platelet aggregation involves a set of medical devices, which
allow precise control over the dynamic differential rate of blood
flow control along with the extent of platelet thrombus formation.
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The platelet aggregation devices market has been segmented based on
device type, platelet function analyzer (PFA), aggregometers,
platelet function centrifuge, platelet collection systems, and
consumables & accessories. PFA is the most commonly used medical
device for platelet aggregation. It is meant for aspirating in-vitro
blood from the sample into cartridge test via a microscopic aperture,
which is cut into biologically active collagen or epinephrine
membrane on capillary ends. The PFA test reveals platelet function
and number along with other specific elements.
On the basis of end users, platelet aggregation devices market can be
segmented into hospitals, diagnostic laboratories, medical research
institutes and CROs, other end users (blood banks, companies engaged
in clinical trials for platelet disorders). Geographically, North
America (U.S and Canada) dominate the platelet aggregation devices
market followed by Europe as leading manufacturers of platelet
aggregation devices are domiciled in these regions having majority of
their operations in local regional markets. However, Asia Pacific is
also one of the key lucrative markets for these devices for
diagnosing epidemic diseases such as Dengue, Malaria that affect a
huge chunk of population in this region.
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The potential drivers for this specialized and niche market includes
massive unmet demand for platelet screening programs to identify
diseases like HIV, Dengue etc. However, there is certainly a clear
market demand among those undergoing anti-platelet therapy. On
account of being a medical device market, the key forces for growth
would depend upon product features such as precise control over the
extent of platelet thrombus and spatial location, minimal blood
sample volumes along with multiple clinical assessment’s, and
simplified precise procedures. Besides, these factors Platelet
Aggregation devices have a wide range of applications in diagnosing
various diseases, detecting platelet dysfunction, and associated
disorders. The demand for Platelet aggregation devices will be
further spearheaded with a wide range of new applications such as
assessment of surgical bleeding risk, identification of genetically
acquired platelet defects etc. However, some of the restraints in
this foresighted growth will be attributed to the high cost of
purchase, limited usage, and limited scope at the level of end users.
Some of the key players operating in the platelet aggregation devices
market include Bio Data Corporation, Drucker Diagnostics, Haemonetics
Corporation, Helena Laboratories, F. Hoffmann-La Roche Ltd.,
Laboratory Corporation of America Holdings (LabCorp), Siemens
Healthcare, Sienco, Inc., and Sysmex Corporation among others.
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