Single-use bioreactors, which are ideally suited for manufacturing
biopharmaceutical products because of their high-performance, have
become highly evolved these days thanks to constant efforts by
players to develop products. They are seen working on improving
designs, sensor systems, film technology, and stirring mechanism of
single-use bioreactors. In doing so, they are factoring in the
specific requirements of their clients vis-à-vis gene and cell
therapies and for continued bioprocessing.
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Some of the prominent participants in the global single-use
bioreactors market are Stedim Biotech, Sartorius Merck Millipore,
Thermo Fisher Scientific, GE Healthcare, Celltainer Biotech, Danaher,
Applikon Biotechnology, Parker Hannifin, Cesco Bioengineering, PBS
Biotech, Cellexus, Distek, Pierre Guerin, Eppendorf, and Solida
Biotech.
Transparency Market Research (TMR), which recently prepared a report
on the global market for single-use bioreactors, finds that it is
primed for good growth over the course of the forecast period between
2017 and 2026. It states that by registering a CAGR of 13.5%, the
market will likely reach a value of US$1.55 bn by the end of 2026.
The different types of single-use bioreactors available in the market
are media bags, filtration assemblies, and single use bioreactor
systems. The single use bioreactor systems of them are expected to
expand at a healthy clip in the next couple of years. Media bags form
another attractive product segment and together with single use
bioreactor systems, is expected to generate over half the revenue in
the market.
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North America, Latin America, Europe, Asia Pacific, and the Middle
East and Africa are some of the prominent regions in the global
market for single-use bioreactors. Europe, of them, leads the market
because of the presence of some of the well-known pharmaceutical
companies in the region. Supportive policies meant to boost efforts
by biopharmaceutical companies to come up with new therapies in
biologics is also benefitting the market in the region along with the
rising application of single-use bioreactors in cell culture-based
manufacturing.
Commercial considerations are mostly driving the use of single-use
bioreactors. Manufacturers are keen to ensure that their products
bring about cost savings in biopharmaceutical companies. “While
single-use bioreactor bags are generating pathways that can
manufacture protein-based drugs securely, the compounds or materials
have a tendency to leak on account of the extrusion process that
makes the bag films thin. Fixing of such risks by stabilizing the
materials has spelt new opportunities for savvy companies trying to
increase their sales,” explains the TMR analyst who prepared the
report.
Depending upon end user, the biopharmaceutical companies are
predicted to generate maximum demand. Currently, players are focusing
on designing new generation single-use bioreactors, keeping in mind
the final drug product required by end users.
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Recent developments in single-use bioreactors by manufacturers are
focused on improving mixing, bringing down complexity, and avoiding
leakage, and other integrity issues. Apart from that, bettering
cell-culture processes are also driving rising adoption of single-use
bioreactors.
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