Huge Investments in Development of Biochips Technology

Biochips are a collection of microarrays or micro-test sites fixed on a solid substrate to perform multiple tests at the same time for achieving enhanced speed and throughput. They are small, wafer-like components that are made from substrates such as soda glass, fused quartz, silicon, and plastic. Biochips are effectively a miniature laboratory that functions to perform several biochemical reactions simultaneously.

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The positive growth rate in the global biochips market will be due to the rising investments in biochips technology along with their enhanced diagnostics applications. Furthermore, greater automation with the help of biochips is also likely to propel the overall market in the coming years.

The global biochips market is segmented on the basis of type, application, and geography. On the basis of type, this market is segmented into DNA chips, protein chips, and microfluidic devices. The applications of biochips are seen in genomics, drug discovery and development, proteomics, and in vitro diagnostics. Geographically, this market is segmented into North America, Europe, Asia Pacific, and Rest of the World.

Among the various types of biochips, the DNA chips accounted for 40% of market. The key growth driver supporting this growth is the rising application of biochips in gene expression profiling, drug discovery, toxicological research, DNA sequencing, alternative splicing detection, and diagnostics and genetic engineering.

Amongst the applications, the drug discovery and development segment emerged as the leader with a share of 30% in the global biochips market. The high incidences of various health issues and the need for the development of new medicines and drugs for treatment are the main undercurrents deciding the flow of this segment in the overall market.

Geographically, North America led the overall market with Asia Pacific in tow. Analysts predict that Asia Pacific is expected to offer several growth opportunities to the biochips market in the coming years along with Rest of the World. Demand from emerging economies of South Africa, Brazil, UAE, Japan, China, and Australia are expected to drive this market in the aforementioned regions.

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The key operators in the global biochips market are Affymetrix Inc., Fluidigm Corporation, Illumina Inc., Cepheid Inc., Agilent Technologies Inc., and GE Healthcare Ltd. amongst others. The research report profiles these players and provides a complete analysis of the competitive landscape of the global biochips market. The report also includes an explanation of the investment infrastructure, research and development strategies, feasibility of new projects, business and marketing strategies, and expansion plans of these top players in the global biochips market.

The biochips market has been segmented as:

Global Biochips Market: By Type

> DNA Chips

> Protein Chips

> Microfluidic Devices

Global Biochips Market: By Application

> Drug Discovery & Development

> Genomics

> Proteomics

> In Vitro Diagnostics

Application of Biochips in Drug Discovery & Development, Genomics and In Vitro Diagnostics

Biochips are a collection of microarrays which are arranged on a solid substrate that enables numerous biochemical reactions such as decoding of genes in a few seconds. In addition, biochips are designed to function in biological environments and are capable of detecting and measuring a large number of biomarkers and perform complex biochemical reactions simultaneously in a very short span of time. Biochips are capable of performing a multitude of biochemical reactions simultaneously and with ease. Furthermore, these chips also help in identifying gene sequences and analyzing proteins in human and animal bodies. In in vitro diagnostics, biochips are extensively used to detect the symptoms of diseases and provide effective cures for the same. These chips are also of help in conducting tests for analyzing pandemics, glucose monitoring, drug tests, and diabetic diagnosis, and control of various diseases.

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Biochips enable precise and accurate modelling of physiological situations for fundamental research and drug development, alike. Moreover, the chips also help in carrying out high-volume tests associated with various aspects of drug discovery and development. Furthermore, the advent of biochips has also revolutionized molecular diagnostics in identifying the presence of viruses, bacteria, or other organisms in patient samples for monitoring viral responses to the therapy and detecting genetic disorders.

However, on the flip side, companies involved in manufacturing biochips have to comply with stringent regulations related to medical devices such as United States Pharmacopeia (USP) and Clinical and Laboratory Standards Institute (CLSI), among others. Such regulations are viewed as major bottlenecks by large companies operating in the market.

Increasing application of biochips in the medical sector for cancer treatment, drug research, and diagnostics is one of the major factors driving the growth of the global biochips market. In addition, factors such as availability of molecular information, automation of biochemical processes through the use of biochips and application of biochips for gene and protein identification are set to drive the global biochips market.

The use of biochips has brought about a transition in the field of drug discovery and research. Biochips have the ability to detect cancer before its symptoms develop in human bodies. In addition, it can easily detect virulent diseases such as smallpox, anthrax, and plague in a very short span of time. Moreover, biochips are increasingly finding application in veterinary diagnostics. Biochips comprise grids that may be dots or small wells. Each grid contains nucleic acid or antibodies and proteins which bind to a DNA sequence or a target antigen. The abundance of proteomics and genetics data coupled with the need for identifying gene sequences and proteins in human beings is driving the biochips market. Conventional gene and protein sequencing methods cannot provide qualitative output and are ineffective whereas biochips are extremely effective and produce accurate gene sequencing results in a very short span of time. Significant growth in the healthcare sector, rising demands for diagnostics and increasing medical expenditure coupled with economic reforms in major developing countries has been able to bolster the growth of Biochips market.

Biochips

Use of Biochips has brought about a transition in the field of Drug Discovery and Research

 Biochips Market

The development of biochips has been able to influence the growth of automated processes and miniaturization of products throughout all major sectors covered in report. In the healthcare sector, biochips are largely used in laboratories for drug discovery and research for symptoms of diseases. The laboratory equipments have become smaller and efficient due to the use of biochips. In addition, biochips are capable of performing multiple biochemical reactions simultaneously and easily. Moreover, it helps in identifying and detecting gene sequences and analyzing proteins in animal and human bodies. Biochips are largely used in in-vitro diagnostics, where it detects symptoms of diseases and provides cure for the same. It is also capable of carrying out tests for analyzing pandemics, drug tests, glucose monitoring, diabetic control and diagnosis of various diseases. In addition, biochips ensure accurate and precise modelling physiological situations for both drug development and fundamental research. Moreover, it helps in carrying out high volume tests for numerous aspects in drug discovery and development. In the dynamic business environment where numerous technological advancements are taking place each day, it is necessary for the biochips manufacturing companies to align its strategies with the technological shifts in order to achieve a sustainable growth and profitable returns. Moreover, the use of biochips has revolutionized molecular diagnostics in identifying the presence of organisms such as bacteria and virus in patient samples, detecting genetic disorders and monitoring of viral responses to therapy. Home monitoring biochip systems are expected to detect and provide healthcare solutions with the help of computers to patients in their homes. For initial advice regarding treatment, biochip-enabled computer systems would be able to transmit to the hospital using wireless telemetry, thereby providing the individual with a suitable cure without any delay and effort.

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However, there are a few factors, which are inhibiting the growth of biochips market globally. Companies that manufacture biochips have to comply with a number of regulations relating to medical devices such as Clinical and Laboratory Standards Institute (CLSI) and United States Pharmacopeia (USP) among others, which poses a major challenge for a large number of companies. Microarrays, which are a two-dimensional grid of biosensors, are the essential components of biochips. The sensors are placed on a solid substrate that may be active or passive. Passive substrates are either silicon or glass, which are largely used because silicon and glass have well-established micro fabrication and micromachining processes. Passive substrates require silica etching, which is a time consuming process and entails the use of special resources and a large amount of chemical solvents that pose a threat to environmental safety. The environmental hazards related to the use of glass and silicon as popular substrates for biochips are expected to inhibit the global biochips market significantly.

The biochips market has huge scope and opportunity in the emerging markets of Asia Pacific and Rest of the World (RoW). Countries such as India, China, Japan, and Australia are the key biochips markets falling under the Asia Pacific and RoW regions. Biochips are increasingly finding application in the biotechnology and biomedical devices industries. Molecular diagnostics and drug discovery are the major driving factors influencing the growth of the industries. Moreover, venture capital firms globally are investing heavily in biochip technology.

In North America, the U.S. has been showing significant growth over the years and is one of the dominant biochips markets globally. Japan, China and India are the largest contributors to the biochips market in the Asia Pacific region. In Europe, Germany and U.K. are the largest regional markets for biochips because of increasing investments in biochips technology and growth in the healthcare sector. Latin America and UAE are showing substantial growth and are expected to be key markets in the coming years.

Key participants in the industry include Affymetrix Inc. (U.S.), Illumina Inc. (U.S.), GE Healthcare Ltd. (U.K.), Cepheid Inc. (U.S.), Fluidigm Corporation (U.S.) and Agilent Technologies Inc. (U.S.) among others.

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