Ischemia is characterized by a specific condition, where there is an
insufficient flow of blood supply to tissues, leading to a shortage
of oxygen and glucose which is needed for cellular metabolism. Due to
an obstruction and insufficient blood supply, various organs and
tissue get severely damaged. Ischemia, if left untreated, may lead to
tissue death. Ischemia is primarily caused by thrombosis of an
artery, embolism, vasculitis, atherosclerosis, coronary artery
disease and peripheral artery disease. There are various types of
ischemia with different diagnosis and treatment methods involved with
each type of ischemia.
Based on the types, ischemia market can be segmented as follows:
> Myocardial ischemia: Due to blockage of a coronary artery, there
is a limited blood flow to the heart muscle and is referred to as
myocardial ischemia. Symptoms include arm pain, chest pain,
breathlessness, dizziness, weakness, heart palpitations and clammy
skin.
> Cerebral ischemia: Cerebral ischemia occurs when there is a
temporary deficiency of blood supply to an individual’s brain.
Symptoms include difficulty in speaking, lack of coordination, body
movement problems, vision impairment and unconsciousness.
> Intestinal ischemia: Ischemia affects intestine too, and this
condition is known as intestinal ischemia. Various symptoms include
abdominal pain, fever, diarrhea, vomiting, bloody stools and weight
loss.
> Hepatic ischemia: In hepatic ischemia, an individual’s liver
does not receive enough blood supply. Hypotension is the prime cause
of hepatic ischemia and symptoms include dehydration, heart failure,
severe bleeding and abnormal heart rhythms.
> Acute limb ischemia: Decreased level of blood flow to hands,
feet and legs leads to acute limb ischemia. Symptoms include skin
ulcers, skin sores and severe pain.
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Based on treatment, the ischemia can be segmented as follows:
Medications:
> Angiotensin-converting enzyme (ACE) inhibitors
> Anticoagulants
> Aspirin
> Analgesics
> Beta blockers
> Nitroglycerine
Surgery methods:
> Angioplasty, also referred to as percutaneous coronary
intervention (PCI)
> Coronary artery bypass surgery
> Embolectomy
> Aortomesenteric bypass and resection of bowel
Based on geography, the ischemia market can be segmented into four
major regions: North America, Europe, Asia Pacific and Rest of the
World (RoW). Out of these regions, North America dominates the
ischemia market followed by Europe. The prime factors which would
drive the growth of the market in these regions are growing
prevalence of high cholesterol diseases, increasing incidences of
obesity and physical inactivity. Moreover, technological advancements
and increasing competition from small market players have further
fueled the growth of ischemia market. According to a survey,
approximately 1.5 million cases of myocardial ischemia occur annually
in the United States. Moreover, technological advancements and
increasing competition from small market players have further fueled
the growth of ischemia market. Asia Pacific is one of the most
promising markets for the growth of ischemia market due to easy
market penetration.
The factors which would augment the growth of the market in Asia
Pacific are increasing geriatric population, high prevalence of
unhealthy lifestyle amongst the population and increasing awareness
regarding the malignant effects of ischemia. Other factors such as
tax benefits and increasing disposable incomes of the population
would further propel the growth of ischemia market.
Various biopharmaceutical companies are constantly coming up with
novel therapeutics for the treatment of ischemia. Some of the top
players operating in the ischemia market are Sanofi, Pfizer, Inc.,
Medicure, Inc., Baxter International, Boston Scientific Corporation,
Vasade Biosciences, Inc. and others.
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