Thursday, 8 December 2016

C-Reactive Protein - An Immunoprotein Synthesized in Liver and plays an Important role in Activation of the Complement System

C-reactive protein (CRP) plays a central role in the initiation of the complement system. CRP is an immunoprotein that is synthesized in the liver and under normal circumstances, is expressed at low levels, but increases 1,000 fold within a span of 24 hours of tissue damage. Infection, trauma, certain kinds of cancer, and inflammatory arthritis are some of the common causes of increased levels of c-reactive protein (CRP). As per recent studies, the levels of CRP may rise due to arteriosclerosis in which an inflammatory response is initiated by damaged blood vessels.

Constant technological advancements and improvements in research and development activities in the field of biotechnology have made processes more efficient and, hence, specific. Leading players are focusing on introducing new c-reactive protein tests to contribute further towards the growth of the global c-reactive protein testing market in the years to come. A new test, known as high sensitivity c-reactive protein test (hs-CRP) is more sensitive in nature as compared to the standard CRP test. The new hs-CRP test can easily measure levels of c-reactive proteins in mg/L of the blood. As per an article published in 2012 in The Wall Street Journal, the American Heart Association and American College of Cardiology has endorsed the new test.

According to the World Health Organization (WHO), around 17 million people die of cardiovascular diseases per year. As per European Cardiovascular Disease Statistics, around 47% of global mortalities are caused due to cardiovascular disease in Europe alone. A similar situation exists in many other areas of the world, where the timely diagnosis of a cardiac disorder may reduce the mortality rate. CRP tests are also advised for autoimmune diseases, stroke, osteomyelitis, and post-surgery infections. Today, stroke has also become a major health concern. As per the Stroke Association, U.K., approximately 1.1 million people in the U.K. have survived a stroke in the recent past.


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The global c-reactive protein testing market is expected to expand at a rapid pace in the years to come due to the rise in the number of applications of CRP. The growing volume of c-reactive protein tests performed globally is expected to propel the global c-reactive protein testing market in the next few years. For diagnostic purposes, currently various ELISA, chemiluminescence immunoassay (CLIA), and immunoturbidimetric-based assays are available. Better market penetration is predicted to propel the global c-reactive protein testing market in the next few years.

Some of the leading players in the global c-reactive protein testing market are Randox, Life Technologies, EMD Millipore, and Roche Diagnostics. Based on geography, the global c-reactive protein testing market is divided into North America, Asia Pacific, Europe, and the Rest of the World.

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