Mass Spectrometry - Technique to Analyze Chemical Contents in a Sample Based on Mass-to-Charge Ratio of the Ions

Spectroscopy deals with the study of the interaction between electromagnetic radiation and matter. It is widely used in analytical chemistry in order to identify the contents in a test sample taking help of the interaction between energy and mass. Spectroscopy has been broadly classified on the basis of the method of analyzing the test sample into molecular spectrometry, mass spectrometry, and atomic spectrometry. Among these types, the mass spectroscopy segment is the most used technique to determine the chemical contents in a sample.

Gas chromatography-mass spectrometry (GC-MS) combination systems provide quantitative analysis of the components along with mass spectrum. GC-MS systems find applications in pharmaceutical and chemical analysis, food and product safety, clinical and toxicology testing, and forensic and environmental studies.  MALDI-TOF mass spectrometer uses a focused laser beam in the ultraviolet or infrared range to analyze solid samples in two stages: desorption of surface particles by laser beam and ionization of matrix (solvent). The technique is useful in clinical diagnostics, environmental and taxonomical research, food processing and quality control. Triple-quadrupole liquid chromatography-mass spectrometry is used in pharmaceutical research for pharmacokinetic screening, metabolite identification, impurity profiling and other related applications. The technique is also used in analyzing samples for identifying drug and pesticide residues, identification and quantification of disease agents and carcinogens in food samples. In environmental sciences, it is used for identification of contaminants in water and soil. Inductively coupled plasma mass spectrometry (ICP-MS), a type of mass spectrometry technique, enables the detection of metal components in extremely low concentration and is majorly used for clinical and forensic applications where traces of metals are detected in samples such as urine, plasma and tissue fluids.

In the last few years, the increasing research and development activities in proteomics, molecular biology, gene expression studies, drug development, and biomarkers have boosted the demand for mass spectroscopy. Thus, several mass spectroscopy device manufacturers are focusing on developing the technology.

Future Market Analysis of Mass Spectroscopy is available at:
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The technological advancements in this field are also driving the global market for mass spectroscopy. In addition, these developments have also increased the applications of mass spectroscopy in the last few years. As a result, the customer base has increased tremendously for the global mass spectroscopy market. Some of the major customers in the healthcare sector include research institutions, diagnostic and forensic laboratories, and pharmaceutical companies.

Some of the prominent players operating in the market are Bruker Corporation, Danaher Corporation, Kore Technologies, Ltd., Waters Corporation, Leco Corporation, Dani Instruments S.P.A., Perkinelmer, Inc., Agilent Technologies, Inc., Shimadzu Corporation., and Thermo Fisher Scientific, Inc.

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