High
throughput screening (HTS) is a drug discovery technique employed for
screening and evaluation of large number of biological modulators and
effectors against selected target. Over last two decade, high
throughput screening has gained a widespread popularity and has
become a standard method of drug discovery in the pharmaceutical
industry. The prime goal of high throughput screening technique is to
accelerate drug discovery process by screening large number of
compound libraries such as combinatorial chemistry, genomics,
protein, and peptide libraries at a rate that may exceed a few
thousand compounds per day or week. High-throughput screening methods
are also used to characterize metabolic, pharmacokinetic and
toxicological data for new drugs and thereby eventually reducing the
cost of the drug development. High throughput screening comprises of
several steps such as target identification, reagent preparation,
compound management, assay development and high-throughput library
screening.
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Future Technological Breakthroughs of High Throughput Screening
Market at:
Technological
advancements such as automation of liquid handling, creation of novel
technological platforms, and development of analytical tools to deal
with massive quantities of data has exponentially driven the global
market for high throughput screening devices market in past few
years. Increasing competition among pharma companies with respect to
pioneering drug discovery and commercialization demand for high
throughput screening devices is increasing at a rapid pace. HTS
market promises affirmative growth potential in near future due to
its inevitable use in the research and production field.
Increasing
capital investment in high throughput screening technology by
research organizations and key players operating in market has
boosted the growth and demand in past one decade. Label free methods,
automation & miniaturization of technique and growth of contract
research organizations in emerging market have further escalated the
demand and procurement of instruments across the globe. High capital
requirement for initial set up and maintenance cost are among the
major restraints hampering the growth of the market. Navios Flow
Cytometry System introduced by Beckman Coulter in 2013 and BioTX Pro
Automated Work station launched by PerkinElmer in 2013 are among few
of the new products launched in the market.
Some
of the technological advances in the HTS industry attribute to
introduction of high content screening technologies, robotic
automation, miniaturization of the HTS technological platforms and
novel cell culture approaches. High throughput screening market by
technology can be sub-segmented into four major categories: cell
based assays, ultra high throughput screening (UTHS), lab-on-a-chip
(Loac), label free technology and bioinformatics. Key application
areas of high throughput screening devices include target
identification, primary screening, toxicology and stem cells.
Moreover market by end users can be further sub-segmented into
pharmaceutical sector, biotechnology sector, contract research
organizations, environmental laboratories and academic institutes.
Geographically,
market for high throughput market in terms of revenue is majorly
contributed by developed regions such as North America and Europe
owing to increasing collaboration between manufacturers and research
institutes and organizations. Additionally government initiatives and
investment in drug discovery over past one decade have further driven
the market in both of the developed regions. Asia Pacific and Rest of
the World market are among the fastest growing market pertaining to
increasing demand for cost effective drugs, increasing incidences of
chronic and life threatening diseases and growing economy are among
the prominent drivers escalating growth of high throughput screening
market in emerging economic countries. Some of the prominent players
operating in the market include Agilent Technologies, Inc., Bio-Rad
Laboratories, Perkinelmer, Inc., Tecan Group Ltd., Aurora Biomed,
Sigma Aldrich Corporation, Thermo Fisher Scientific, Inc. and Axxam
Spa.
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