Elastography, a medical imaging technique similar to ultrasound and
MRI, is widely used to detect the hardness and softness of tissue,
which is further used to analyze the presence of diseases along with
stage of development. Transient elastography is a non-invasive
technique used to detect liver fibrosis. Liver fibrosis or stestosis
causes stiffening of liver which is a prime indication of conditions
such as cirrhosis and hepatitis. The principle behind the mechanism
of transient elastography devices is measuring the shear wave
velocity by providing one dimensional image of the tissue. The wave
passes through the tissue which creates a distortion in the tissue.
The motion of the tissue creates an image, which helps to determine
the condition. Ultrasound waves of 5 MHz and low frequency elastic
waves of 50 Hz, whose velocity is directly related to elasticity, are
used in this technique. The stiffness of liver is measured in volume
which is approximately like a cylinder, 1 cm wide and 4 cm long, 25
mm to 65 mm just below the skin. The volume thus measured by the
technique is 100 times bigger than a biopsy sample and is more
accurate. A device called FirbroScan is widely used in transient
elastography technique for clinical management of patients with liver
disease such as chronic hepatitis C and B and fatty liver disorders.
FibroScan was approved by the U.S. FDA in April 2013 to be used in
the detection of diseases. Initially, the device was introduced in
Europe in 2003 and later it was approved in China in 2008, Brazil in
2010, and Japan in 2011. Increase in demand for alternative
non-invasive methods to detect liver fibrosis has made transient
elastography one of the promising techniques for diagnosis of liver
related diseases.
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Rise in sedentary lifestyle, unhealthy dietary habits, and excess
consumption of alcohol have increased the number of individuals with
liver disorders. This in turn drives the diagnosis rate of liver
cirrhosis and fibrosis. Additionally, rise in awareness among the
population about early diagnosis of liver-related diseases fuels the
growth of the transient elastography device market. The transient
elastography technique is best to be performed in patients who have
nonalcoholic fatty liver disease and where liver biopsy cannot be
done. However, high cost of the device and diagnosis procedure along
with technological failure to detect the intermediate stages of
fibrosis act as restraints of the global transient elastography
device market.
The global transient elastography device market can be segmented
based on technology, modality, end-user, and region. In terms of
technology, the market can be divided into vibration controlled
transient elastography (VCTE) and controlled attenuation parameter
(CAP). VCTE helps the device to generate quantitative measurements of
key liver parameters such as liver stiffness. CAP technology is used
to measure the changes in amplitude of ultrasound waves. Based on
modality, the global transient elastography devices market can be
bifurcated into standalone and mobile. In terms of end-user, the
market can be categorized into diagnostic centers, hospitals, and
ambulatory surgical centers. In terms of region, the global transient
elastography device market can be segmented into North America,
Europe, Asia Pacific, Latin America, and Middle East & Africa.
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North America projects a slow adoption of the technique. The U.S. has
witnessed a slower adoption over usage of non-invasive test for liver
disease and continues with the traditional approach of liver biopsy.
Europe and Latin America are promising markets for technique as
non-invasive techniques are replacing the traditional biopsy method
in evaluating liver disorder in Europe and Latin America. According
to the European Association guidelines for the Study of the Liver and
Association of Latino Americana para el Estudio del HÃgado, all
available non-invasive alternatives to liver biopsy, either patented
or non-patented, should be used for both viral and non-viral chronic
liver diseases. Asia Pacific is also a potential market for transient
elastography technique for liver disease. This technique is widely
used in China, Canada, Japan, and Brazil. Both India and the U.S. are
high potential markets for transient elastography devices. Middle
East & Africa has recorded slow adoption of transient
elastography technique due to high cost and sluggish growth of the
health care industry.
Key players in the global transient elastography device market are
Echosens and Sandhill Scientific, Inc., among others.
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