TNF (tumor necrosis factor) inhibitors are anti-inflammatory drugs.
TNF inhibitors help to block the TNF alpha that occurs naturally in
the body and causes inflammation. TNF drugs are used to reduce
inflammation and stop disease progression by targeting the tumor
necrosis factor, which is an inflammation-causing substance. TNF
inhibitor drugs are employed to treat inflammatory conditions such as
rheumatoid arthritis and juvenile arthritis. Generally, in the
healthy person, the TNF levels remain steady. However, in a patient
with rheumatoid arthritis, the level of TNF is increasing which leads
to more inflammation. TNF inhibitor drugs act as blockers for TNF
substances. TNF alpha blockers are highly effective in the treatment
of patients with active rheumatoid arthritis. These drugs are used in
patients as a conventional second-line treatments.
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Based on drug, the TNF inhibitors market can be segmented into
etanercept, infliximab, adalimumab, certolizumab, and golimumab. The
adalimumab segment is likely to expand at a significant pace during
the forecast period. The drug is effectively used in a broad range of
pain management therapies and is widely available over the counter.
Based on distribution channel, the TNF inhibitors market can be
segmented into hospital pharmacy and retail pharmacy. The hospital
pharmacy segment is likely to expand at a significant pace between
2017 and 2025, this is because patients with rheumatoid arthritis,
arthritis give more preference to the hospitals for treatment.
Increase in elderly population and rise in the prevalence of
rheumatoid arthritis, psoriatic arthritis, and inflammatory bowel
disease are some of the factors that drive the TNF inhibitors market.
According to the National Health Interview Survey, in 2016, almost
20% of the global population was reported to be suffering from
chronic pain, with rheumatoid arthritis being one of the major
reasons. Moreover, according to the Center for Disease Control and
Prevention, by 2040, approximately 78 million (26%) of the U.S.
adults are projected to have arthritis. Owing to this, the
consumption of TNF inhibitor dugs is likely to increase rapidly in
the near future. However, side-effects associated with the use of TNF
inhibitor drugs such as skin irritation, flushing, headache, and
abdominal pain are estimated to hinder the market in the next few
years.
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In terms of region, the global TNF inhibitors market can be segmented
into North America, Europe, Asia Pacific, Latin America, and Middle
East & Africa. North America is the leading market share,
primarily due to favorable reimbursement policies for pain management
prescription drugs in the region. Lenient regulations in Europe are
playing a key role in the increased rate of development, approval,
and commercialization of innovative molecule combinations in the pain
management. This is likely to fuel the market in Europe during the
forecast period.
The increasing prevalent population and launching of new products are
estimated to drive the market in Asia Pacific during the forecast
period. Despite sustained growth and development Middle East &
Africa had faced several health challenges over the last decade.
Factors such as economic resources, adequate health care facilities,
and growing burden of communicable diseases are likely to propel the
market in the region from 2017 to 2025. Moreover, rheumatology
services are limited or non-existent in several parts of sub-Saharan
Africa. Hence, making these services available may boost the market
in Middle East & Africa during the forecast period.
Major players operating in the global TNF inhibitors market are
Pfizer, Boehringer Ingelheim, Novartis, Amgen, Mochida
Pharmaceutical, Hanall, BioPharma, GalxoSmithKline, and Janssen
Biotech.
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