Maintaining aseptic conditions in the pharmaceutical and medical
industry is of utmost importance in order to avoid any contamination
to product. Cleanrooms provide this feature, but in most of the cases
these incur high capital. Restricted barrier access system (RABS),
introduced around 1995, is a setup which isolates the operator from
the operational area, as humans (operator) are supposed to be the
major carriers of contaminating agents. Since its introduction, RABS
systems have found applications in industries such as pharmaceutical,
medical, and chemical. RABS setup provides protection by physical
barrier and dynamic airflow. RABS have posed as an effective
alternatives the conventional isolators in terms of cost and
efficiency. According to guidelines set up by the International
Society for Pharmaceutical Engineering (ISPE), RABS system should
provide an airflow of ISO5, it should provide physical barrier for
human interventions in the critical zone, and have automated
processes and procedures.
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Demand for RABS system is expected to rise in the next few years
driven by features such as provision of aseptic safety in critical
zone of an isolator and flexibility for interventions like cleanroom.
Moreover, efficiency and less capital investment compared to isolator
and cleanroom are expected to propel demand for restricted access
barrier system in the near future. The rules and regulations for
manufacturing procedure are getting stringent with demand for aseptic
and efficient pharmaceutical and medical products, also with need for
safety in research and development and manufacturing from toxic and
viral product agents is rising which is expected to drive the
business for restricted access barrier systems in near future.
However, high cost of installation and components and high cost of
maintenance are expected to hamper the growth of the global RABS
market. Additionally, limited number of suppliers and requirement of
trained operators are expected to restrain the global restricted
access barrier system market.
The global restricted access barrier system market can be segmented
based on type of ventilation and air outlet. Based on type of
ventilation, the market can be segmented into passive RABS and active
RABS. Passive RABS uses filtered and purified air from cleanroom.
This system does not have its own air filters and air conditioning
system. Active RABS uses HEPA filter incorporated in the system to
provide filtered air and even air-flow distribution in critical area.
In terms of air outlet, the market can be segmented into open RABS
and closed RABS. Open RABS spills the air passed through its critical
zone into cleanroom without any further filtration. While closed RABS
recirculates the critical area passed air to its HEPA filters and
spills the filtered air into cleanroom. Most of the active RABS
setups are closed systems.
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In terms of region, the global restricted access barrier system
market has been segmented into North America, Europe, Asia Pacific,
and Rest of the World. North America is expected to account for major
share of the global RABS market. The market in the region is expected
to expand at a higher rate owing to presence of major pharmaceutical
and biotechnology organizations and demand for safe, aseptic, and
standard manufacturing and research processes. Europe is expected to
be the second largest market for restricted access barrier system
driven by growing industry and stringent manufacturing rules and
regulations. The restricted access barrier system market in Asia
Pacific is expected to witness strong growth in the near future
attributed to emerging economies such as China and India.
Major players in the global restricted access barrier system market
are IMA S.p.A., AZBIL TELSTAR, S.L.U., Comecer S.p.A., Robert Bosch
GmbH, Extract Technology, Ortner Reinraumtechnik GmbH, Germfree,
Tofflon Science and Technology Co., Ltd., and Isolation Systems,
Inc., among others.
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