Bipolar disorder, also known as manic-depressive disorder, is a
mental illness. It is a mental health problem that primarily affects
mood. Symptoms of bipolar disorder are extreme irritability or
agitation, a period of feeling empty, loss of interest in normal
activities, sleep problems, etc. According to Pfizer, Inc., bipolar
disorder affects over 5 million people in the U.S. Bipolar episodes
are characterized by a drastic change in behavior and mood, and range
from joyful and overexcited (manic episodes) to extremely sad and
hopeless (depressive state). These disorders have different types of
episodes such as manic episodes, hypomanic episodes, depressive
episodes, and mixed episodes.
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Causes of bipolar disorders include childhood trauma, stressful life
events, self-esteem problems, and genetic inheritance. People across
the world marked “March 30” as a World Bipolar Day to spread
awareness about the disorder and erase the stigma of mental illness.
Large number of people suffering from this mental condition resort to
drinking to lift their mood. According to the National Institute on
Alcohol Abuse and Alcoholism, 27.6% of the people with bipolar
disorder become addicted to alcohol, while over 16% engaged in
alcohol abuse.
Rise in prevalence of bipolar disorder, high unmet medical needs,
technological advancement and government initiatives are the key
factors accelerating the growth of the bipolar disorder therapeutics
market. According to the National Institute of Mental Health, in
2016, the Johns Hopkins University School of Medicine and the Salk
Institute for Biological Studies co-led a US$ 15.4 Mn effort to
develop new systems for quickly screening libraries of drugs for
potential effectiveness against schizophrenia and bipolar disorder.
Increase in investment in research and development and collaboration
activities between companies for product development are the other
factors likely to propel the bipolar disorder therapeutics market. In
2015, Aequus and Corium entered into product development
collaboration focused on CNS diseases such as autistic disorder,
bipolar disorder, schizophrenia, and other major depressive
disorders. However, stringent regulations acts as a major restraint
of the bipolar disorder therapeutics market.
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The global bipolar disorder therapeutics market can be segmented
based on disease type, drug type, distribution channel, and region.
In terms of disease type, the market can be classified into bipolar
I, bipolar II, cyclothymia, and others. Based on drug type, the
global bipolar disorder therapeutics market can be categorized into
mood stabilizers, antipsychotics, antidepressants, and others. In
terms of distribution channel, the market can be divided into
hospital pharmacies, retail pharmacies, and online pharmacies.
Geographically, the global bipolar disorder therapeutics market can
be segmented into North America, Latin America, Europe, Asia Pacific,
and Middle East & Africa.
North America dominates the global bipolar disorder therapeutics
market due to new product innovation, increased awareness among
people about bipolar disease, and rise in prevalence of bipolar
disorders. According to the National Institutes of Health, in the
U.S., 48.8% people with bipolar disorder are receiving treatment.
Europe is the second largest market for bipolar disorder
therapeutics. The market in Asia Pacific is expected to expand at a
higher growth rate due to increase in investment in research &
development, growing awareness among people, rise in investment by
pharmaceutical companies, and availability of skilled manpower for
product manufacturing. According to Graphiq, Inc., per year 100,000
people lost their life from bipolar disorder in India has increased
by 14.3% since 1990, an average of 0.6% a year.
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Major players operating in the global bipolar disorder therapeutics
market include Eli Lilly and Company, AstraZeneca plc, Pfizer, Inc.,
Janssen Pharmaceuticals, Otsuka America Pharmaceutical, Inc., and
Allergan plc.
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