Biosensors are endogenous compounds (lactate and glucose), are used
to monitor cell cultures. Cell cultures are used for several purposes
such as for understanding biological mechanisms in the field of
regenerative medicines and in development of new drugs and therapies.
Since recent years, the new drug development market has been focusing
on targeted drug therapies such as personalized medicines, biologics,
and biosimilars. Targeted therapies are used for the treatment of
chronic diseases such as cancer or rare diseases. Therefore, there is
a need to expedite the development of such medicines. Targeted drug
therapies are patient-specific and require genetic testing. Cell
cultures are used to conduct genetic studies. Cell culture procedures
require periodic monitoring of cell culture in order to ensure
appropriate growth of predetermined cells for testing and analysis
and to avoid contamination.
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These procedures are generally time consuming. Cell culture
monitoring biosensor is defined as “a self-contained analytical
device that conglomerates a physicochemical component with a
biological component for the analysis of suitable analyte of
biological importance.” The biosensors comprise an electrode in
which the sensing element is present. The sensing element reacts with
the desired analyte present in the cell culture and activates the
electrode. Cell culture monitoring biosensors record various
behaviors occurring during the process of cell culture such as
variation in temperature, release of toxic substance, liberation of
desired metabolites, increase in cell density, and occurrence of cell
growth.
Based on electrode type, the global cell culture monitoring
biosensors market can be segmented into thermometric biosensor,
electrochemical biosensor, piezoelectric biosensor, fiber optic
biosensor, and others. The market for electrochemical biosensor is
expected to expand during the forecast period. On the basis of
analyte, the global cell culture monitoring biosensors market can be
divided into adenosine, hypoxanthine, glucose, ionosine, ATP,
lactate, and others. Increase in research of biologics and
personalized medicines has fueled the demand for cell culture
monitoring biosensors. Furthermore, manual cell culture monitoring is
time consuming and increases the risk for contamination.
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Biosensors enable effective monitoring of cell culture growth,
contamination, and byproducts. Thus, increase in demand for
biosensors boosts the growth of the global cell culture monitoring
biosensors market. Moreover, rise in awareness of cell culture
monitoring biosensors and increase in production of
biopharmaceuticals propel the global cell culture monitoring
biosensors market. However, lack of qualified health care
professionals and developed health care infrastructure hampers the
growth of the global cell culture monitoring biosensors market.
In terms of geography, the global cell culture monitoring biosensors
market can be segmented into North America, Latin America, Europe,
Asia Pacific, and Middle East & Africa. North America and Europe
dominated the global cell culture monitoring biosensors market due to
rising percentage of population suffering from chronic diseases. In
addition, presence of developed health care infrastructure and
increase in demand for targeted therapies such as biologics have
accelerated the growth of the global cell culture monitoring
biosensors market in these regions. Asia Pacific is an emerging
market due to the increase in incidence of chronic diseases, rapid
development of health care infrastructure, rising awareness about
advanced treatment options, and increase in government expenditure in
the health care sector. However, poorly developed health care
infrastructure and high cost hamper the growth of the global cell
culture monitoring biosensors market in Middle East & Africa.
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Major players operating in the global cell culture monitoring
biosensors market include PreSens Precision Sensing GmbH, Nova
Biomedical, Conductive Technologies Inc., Lonza, CCIT Sensors AG,
Nanomedical Diagnostics, Sierra Sensors GmbH, and Lifeonics.
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