DNA sequencing is defined as the process of determining the order of
four nucleotide bases i.e. adenine, guanine, cytosine and thymine
within the strand of deoxyribonucleic acid (DNA) molecule. DNA
sequencing technology is extensively used for drug development since
its success in the human genome project, making it an essential tool
for genetic analysis. Additionally, innovations in the microarrays,
bioinformatics and other important tools have increased the area of
application and services of DNA sequencing in drug discovery. On the
basis of sequencing tools, DNA sequencing in drug discovery market is
fragmented into four major segments namely instruments, consumables,
services and workflow.
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The market for DNA sequencing in drug discovery can also be analyzed
on the basis of consumables used during the procedure. Various types
of consumables such as chemicals, reagents and probes, DNA
polymerase, primes and automated DNA sequencers are being used in DNA
sequencing process.
Besides, the workflow in DNA sequencing in drug discovery market
majorly includes bioinformatics software, computational chemistry and
biology modeling. These products aid in increasing the efficiency of
process and understanding of the molecule in study. They can be used
in analyzing and solving chemical problems during the study.
Presently, DNA-sequencing in drug discovery market is focused on
developing drugs for oncology, various vaccines and infectious
diseases. The market of DNA-sequencing in drug discovery is
increasing at a rapid pace majorly driven by increasing applications
of microarrays and polymerase chain reaction techniques and
increasing research and development of personalized medicines.
Moreover, technological breakthroughs and increasing applications of
automated sequencer is also helping the market to grow. The growth of
DNA-sequencing in drug discovery market is restrained by few factors
such as partial scope of microarrays for pathogen enumeration, high
cost of supporting products and incompatibility problems with current
bioinformatics tools.
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North America is currently leading the DNA-sequencing in drug
discovery market followed by Europe majorly due to increasing
government funds towards the associated research and development. In
U.S., the national human genome research institute (NHGRI), part of
national institute of health (NIH) granted more than USD 14 million
in grants for developing new and innovative DNA sequencing
technologies to be used in drug discovery for various fatal diseases.
The Asia-Pacific market will grow at a faster pace owing to
increasing funds by the government of countries such as India, Japan,
China and Australia for research and development activities. Key
players are seeking for market opportunities in potential geographies
such as Asia-Pacific and Latin America, either through organic or
inorganic route. For instance, Thermo Fisher Scientific recently
acquired Life Technologies for USD 13.6 billion in cash which is
sought to have a major impact on the global DNA sequencing industry.
Some of the major key players in DNA-sequencing in drug discovery
market include 454 Life Sciences, Beckman Coulter, Inc., Bio-Rad
Laboratories, Inc., Commonwealth Biotechnologies, Inc., GE
Healthcare, Roche Diagnostics, QIAGEN, Illumina, Inc., GVK
Biosciences Private Limited, Nanogen, Inc., Promega Corporation,
Siemens Healthcare Diagnostics, Sigma-Aldrich Corporation and Thermo
Fisher Scientific, Inc.
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