Oxidative stress is
initiated by the presence of a reactive oxygen species (ROS) which
the cell fails to counterbalance and then it damages the biomolecules
such as DNA, RNA, lipids and proteins. Oxidative stress has been
associated with the aging process as well as various other disease
states.It is an ongoingprocess between highly reactive radicals and
the body system designed for mitigating their effects.Few diseases
occur from a failure to counter these effects. Oxidative stress
causes many pathophysiological disorders in the body and some of
these include neurodegenerative diseases such as Alzheimer’s
disease and Parkinson's disease, cancers, fragile X syndrome, chronic
fatigue syndrome, atherosclerosis, heart and blood vessel disorders,
cardiovascular disease, inflammatory diseases and others.Oxidative
stress assay is a method for detecting and screening markers of
oxidative stress in cells. It is a great tool for analyzing and
evaluating the capacity to counter the oxidative stress as it
provides relevant biological information.
Furthermore,
progresses are made in the field of oxidative stress assay markets
are technologically advanced equipment with updated technologies to
produce high efficiency and accuracy in the testing of oxidative
stress.Rapid growth in the pharmaceutical and biotechnological
industry, robust trend of research and development, investments in
the healthcare sectors, up gradation oftechnology such as content
screening for drug discovery, and government subsidy for life science
research are the prime growth drivers for oxidative stress assay
market. However, there are fewhindrances in the growth of the market;
these arelack of awareness, emerging technologies, increased cost of
instruments and lack of qualified professionals.
The oxidative stress
assay market can be segmented as products, test types, technologies,
end users and disease type.
Product types of
oxidative stress assay market are divided on the basis of consumables
and instruments. Consumables arecategorized as kits and reagents,
buffers and chemicals, microplates and antibodies and reagents. The
consumables segment in the product type is largest inthe market and
is expected to grow at the fastest rate in near future. The main
reason for it are clinical advances and increased use incontract
research organizations (CRO) and biotechnological industries.
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The test type can be
divided as reactive oxygen species (ROS)-based assays and
enzyme-based assays, antioxidant capacity assays.
Based ontechnologies
the market is divided as ELISA, chromatography and microscopy.
Oxidative stress
assay market can be broadly divided into disease types such as
cardiovascular disease, diabetes, chronic obstructive pulmonary
disease (COPD), cancer and asthma.
The end users for
oxidative stress assay market are categorized as clinical
laboratories, pharmaceutical companies, contract research
organizations (CRO) and biotechnological companies.
Geographically the
market for oxidative stress assay market are divided as North
America, Europe, Asia Pacific, Latin America and Rest of the
world.There are some major reasons, responsible for their dominance
in this market are increasing number of aged population and high
levels of public awareness and innovative technologies. North America
and Europe are in the leading position in this market due to their
highly advanced technology and infrastructure compared to the
improving infrastructure in emerging regions. However, Asia Pacific
is estimatedto grow in oxidative stress assay market in future for
number of factors such as government initiatives, growing awareness
and increased investment in healthcare sector.
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Some of the key
players in the oxidative stress assay marketbased on pharmaceutical
and biotechnological companies are Abcam Plc., BioVision, Inc., Cell
Biolabs, Inc., Merck and Co., Inc., Oxford Biomedical Research,
Promega Corporation,Sigma-Aldrich Corporation and Thermo Fisher
Scientific, Inc., while the leading clinical laboratories are
Alliance Imaging, Inc., Array BioPharma Inc., Genoptix, Inc. and
Quest Diagnostics.
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