Topical drug delivery systems are designed to deliver drugs through
topical routes such as the skin, mucosa or cavities in the body.
These are applied locally for site specific action or to avoid first
pass effect of the drug. Skin is the most readily accessible part of
the body with a large surface area and is rich in blood vessels and
porous structures, enhancing the absorption of the drugs. The topical
drug delivery system has witnessed technological advancements over a
period of time and is attracting many researchers to develop novel
products in this area. Common skin diseases that are treated
preferably by topical drug delivery system include bacterial
infections, fungal infections, inflammations and pruritic
manifestations, acne, psoriasis, hair and skin problems, and others.
Nasal mucosa is highly perfused with blood vessels and has been
proven as a site for faster absorption of drugs. Hence, there is
increasing research toward the development of targeted drug delivery
systems for nasal route. Topical is a highly preferred route of drug
administration for the treatment of ocular disorders owing to its
site specific action, reduced first pass metabolism, and faster
action.
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The growing incidence and prevalence rate of tropical diseases is
boosting the growth of the topical drug delivery systems market.
According to the American Academy of Dermatology, in the U.S., about
50 million people are affected by acne each year. The global topical
drug delivery systems market is expected to expand at a fast growth
rate during the forecast period owing to factors such as increasing
number of patients with skin diseases, preference for novel
transdermal delivery systems, growing patient preference towards
topical drugs over oral drugs owing to avoidance of bitter taste of
the drugs taken orally, and desired site specific actions to treat
many disorders. However, high development cost, different solubility
profiles of drugs making product formulation challenging, stringent
regulatory requirements, and difficult testing procedure of final
products are some of the factors restraining the growth of the global
market.
The global topical drug delivery systems market is segmented based on
drug delivery system, route of administration, distributor, and
region. In terms of drug delivery system, the global market is
segmented into conventional drug delivery systems and novel drug
delivery systems. The conventional drug delivery systems segment is
further categorized into solid drug delivery systems, semi-solid drug
delivery systems, and liquid drug delivery systems. The solid drug
delivery systems sub-segment is further divided into powders and
suppositories. The semi-solid drug delivery systems sub-segment is
further categorized into creams, ointments, gels, and pastes. The
liquid drug delivery systems sub-segment is divided into lotions,
sprays, solutions, and others. The novel drug delivery systems
segment includes nanosomes, liposomes, and transdermal patches. Based
on route of administration, the global market is segmented into
dermal, ophthalmic, nasal, oromucosal, rectal, and vaginal. In terms
of distributor, the market is categorized into hospital pharmacies,
retail pharmacies, and online pharmacies.
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Geographically, the global topical drug delivery systems market is
distributed over North America, Europe, Asia Pacific, Latin America,
and Middle East & Africa. North America dominates the global
market for topical drug delivery systems owing to high incidence of
skin diseases, growing awareness about cosmetic care, high health
care expenditure, and growing R&D activities in the transdermal
drug delivery systems by players located in the U.S. Europe is the
second largest market due to growing geriatric population, increasing
R&D investments, and rising adoption of novel drug delivery
systems to treat chronic dermatological conditions. Asia Pacific is
considered as an emerging market owing to higher prevalence of skin
diseases due to unhealthy lifestyle among general population, and
lack of hygiene, along with increasing awareness and accessibility
for topical drugs for treatment of various diseases.
Key players operating in the global topical drug delivery systems
market include GlaxoSmithKline plc, Valeant, 3M, Bayer AG, Novartis
AG, Cipla, Galderma S.A., Pharmatek Laboratories, Mylan
Pharmaceuticals, Inc., Transdermal Technologies, Inc., and Prosollus
Pharmaceuticals.
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